AIMC Topic: Carcinoma, Non-Small-Cell Lung

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[Prediction of gene mutation in lung cancer based on deep learning and histomorphology analysis].

Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi Feb 25, 2020
Lung cancer is a most common malignant tumor of the lung and is the cancer with the highest morbidity and mortality worldwide. For patients with advanced non-small cell lung cancer who have undergone epidermal growth factor receptor (EGFR) gene mutat...
Deep Learning Humans Carcinoma, Non-Small-Cell Lung Lung Neoplasms Mutation ErbB Receptors
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Discussion.

The Journal of thoracic and cardiovascular surgery Nov 1, 2019
Humans Lung Neoplasms Carcinoma, Non-Small-Cell Lung Robotics Robotic Surgical Procedures Propensity Score
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DL-CNV: A deep learning method for identifying copy number variations based on next generation target sequencing.

Mathematical biosciences and engineering : MBE Sep 30, 2019
Copy number variations (CNVs) play an important role in many types of cancer. With the rapid development of next generation sequencing (NGS) techniques, many methods for detecting CNVs of a single sample have emerged: (i) require genome-wide data of ...
Humans Algorithms Databases, Factual ROC Curve Lung Neoplasms Carcinoma, Non-Small-Cell Lung DNA Copy Number Variations Area Under Curve Reproducibility of Results Sensitivity and Specificity Deep Learning Genome-Wide Association Study False Positive Reactions High-Throughput Nucleotide Sequencing Exons Proto-Oncogene Proteins c-met In Situ Hybridization, Fluorescence Receptor, ErbB-2 Genome, Human
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Machine-Learning and Stochastic Tumor Growth Models for Predicting Outcomes in Patients With Advanced Non-Small-Cell Lung Cancer.

JCO clinical cancer informatics Sep 1, 2019
PURPOSE: The prediction of clinical outcomes for patients with cancer is central to precision medicine and the design of clinical trials. We developed and validated machine-learning models for three important clinical end points in patients with adva...
Kaplan-Meier Estimate Stochastic Processes Machine Learning Combined Modality Therapy Algorithms Humans Tumor Burden Prognosis Randomized Controlled Trials as Topic Treatment Outcome Neoplasm Metastasis Lung Neoplasms Neoplasm Staging Molecular Targeted Therapy Carcinoma, Non-Small-Cell Lung Models, Biological
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Predicting response to cancer immunotherapy using noninvasive radiomic biomarkers.

Annals of oncology : official journal of the European Society for Medical Oncology Jun 1, 2019
INTRODUCTION: Immunotherapy is regarded as one of the major breakthroughs in cancer treatment. Despite its success, only a subset of patients responds-urging the quest for predictive biomarkers. We hypothesize that artificial intelligence (AI) algori...
Programmed Cell Death 1 Receptor Antineoplastic Combined Chemotherapy Protocols Carcinoma, Non-Small-Cell Lung Follow-Up Studies Predictive Value of Tests Artificial Intelligence Machine Learning Algorithms Prognosis Survival Rate Lung Neoplasms Immunotherapy Tomography, X-Ray Computed Melanoma Humans
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Validity of Natural Language Processing for Ascertainment of and Test Results in SEER Cases of Stage IV Non-Small-Cell Lung Cancer.

JCO clinical cancer informatics May 1, 2019
PURPOSE: SEER registries do not report results of epidermal growth factor receptor () and anaplastic lymphoma kinase () mutation tests. To facilitate population-based research in molecularly defined subgroups of non-small-cell lung cancer (NSCLC), we...
Kentucky ErbB Receptors Anaplastic Lymphoma Kinase Aged Registries Humans Adult Genetic Testing Machine Learning Male SEER Program Algorithms Middle Aged DNA Mutational Analysis Female Population Surveillance Reproducibility of Results Lung Neoplasms Natural Language Processing Mutation Carcinoma, Non-Small-Cell Lung
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Machine learning-based predictors for immune checkpoint inhibitor therapy of non-small-cell lung cancer.

Annals of oncology : official journal of the European Society for Medical Oncology Apr 1, 2019
Biomarkers, Tumor Male Middle Aged Lung Models, Genetic Carcinoma, Non-Small-Cell Lung Predictive Value of Tests Lung Neoplasms B7-H1 Antigen Machine Learning Aged Aged, 80 and over Adult Mutation Humans Biopsy Programmed Cell Death 1 Receptor Drug Resistance, Neoplasm
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Constructing a Risk Prediction Model for Lung Cancer Recurrence by Using Gene Function Clustering and Machine Learning.

Combinatorial chemistry & high throughput screening Jan 1, 2019
OBJECTIVE: A significant proportion of patients with early non-small cell lung cancer (NSCLC) can be cured by surgery. The distant metastasis of tumors is the most common cause of treatment failure. Precisely predicting the likelihood that a patient ...
Male Models, Biological Middle Aged Humans Multigene Family Lung Neoplasms Machine Learning Recurrence Female Gene Expression Regulation, Neoplastic Risk Factors Carcinoma, Non-Small-Cell Lung
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High serum YKL-40 level is associated with poor prognosis in patients with lung cancer.

Tuberkuloz ve toraks Dec 1, 2018
INTRODUCTION: YKL-40 is a glycoprotein that plays role in inflammation and malignant processes. High serum YKL-40 levels are associated with short survive in cancer and chronic obstructive pulmonary disease (COPD) is another reason to increase its' l...
Lung Neoplasms Adult Adipokines Biomarkers, Tumor Humans Carcinoma, Non-Small-Cell Lung Chitinase-3-Like Protein 1 Neoplasm Staging Male Prognosis Biopsy, Fine-Needle Middle Aged Bronchoscopy Female Glycoproteins Aged
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[Effect of Brucea javanica oil emulsion on proliferation, migration and autophagy of non-small cell lung cancer A549 cells and the underlying mechanisms].

Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences Nov 28, 2018
To investigate the effect of Brucea javanica oil emulsion on proliferation, migration and autophagy of non-small cell lung cancer A549 cells.
 Methods: First, A549 cells were divided into a control group and a low, medium or high dose of Brucea javan...
Plant Oils A549 Cells Autophagy Brucea Lung Neoplasms Humans Cell Proliferation Carcinoma, Non-Small-Cell Lung Cell Movement
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