BACKGROUND: Recurrent pregnancy loss (RPL), characterized by multiple miscarriages, remains a condition with unclear etiology, posing significant challenges for affected women and couples. This study aims to explore the underlying mechanisms of RPL, ...
Major depressive disorder (MDD) is highly heterogeneous, posing challenges for effective treatment due to complex interactions between clinical symptoms and neurobiological features. To address this, we apply contrastive principal-component analysis ...
C2 pars interarticularis length (C2PIL) required for pars screws has not been thoroughly studied in subjects with high-riding vertebral artery (HRVA). We aimed to measure C2PIL specifically on the sides with HRVA, define short pars, optimal pars scre...
Current diagnostic procedures for attention deficit hyperactivity disorder (ADHD) are mainly subjective and prone to bias. While research on potential biomarkers, including EEG, brain imaging, and genetics is promising, it has yet to demonstrate clin...
Diagnosing ASD in adults presents unique challenges, and there are currently no specific biomarkers for this condition. Most existing studies on the gut microbiota in ASD are conducted in children; however, the composition of the gut microbiota in c...
The absence of specific markers makes early detection of bladder cancer (BC) challenging. Recent studies have reported the reliable diagnostic significance of volatile organic compounds (VOCs) in several cancers. This study aimed to investigate wheth...
Environmental pollution (Barking, Essex : 1987)
May 17, 2025
Preterm birth (PTB) is a primary cause of mortality among newborns globally. Prenatal exposure to environmental pollutants has been suggested to increase the PTB risk. Studies have shown NEOs may be linked to adverse birth outcomes. However, the impa...
OBJECTIVE: Neuroserpin, a serine protease inhibitor, is recognized for its anti-inflammatory and neuroprotective properties. Given the central role of inflammation and neurological involvement in the pathophysiology of preeclampsia, this study aimed ...
BACKGROUND: Vascular smooth muscle cells loaded with cholesterol (foam-VSMCs) play a crucial role in the progression of human atherosclerosis. Exchange Protein Directly Activated by cAMP 1 (EPAC1) is a critical protein in the regulation of vascular t...
Cancer control : journal of the Moffitt Cancer Center
May 7, 2025
IntroductionEarly diagnosis of colorectal cancer (CRC) poses a significant clinical challenge. This study aims to develop machine learning (ML) models for CRC risk prediction using clinical laboratory data.MethodsThis retrospective, single-center stu...
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