AIMC Topic: Cell Line, Tumor

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Machine Learning with Optical Phase Signatures for Phenotypic Profiling of Cell Lines.

Cytometry. Part A : the journal of the International Society for Analytical Cytology
Robust and reproducible profiling of cell lines is essential for phenotypic screening assays. The goals of this study were to determine robust and reproducible optical phase signatures of cell lines for classification with machine learning and to cor...

Machine Learning Based Real-Time Image-Guided Cell Sorting and Classification.

Cytometry. Part A : the journal of the International Society for Analytical Cytology
Cell classification based on phenotypical, spatial, and genetic information greatly advances our understanding of the physiology and pathology of biological systems. Technologies derived from next generation sequencing and fluorescent activated cell ...

Predicting DNA Methylation States with Hybrid Information Based Deep-Learning Model.

IEEE/ACM transactions on computational biology and bioinformatics
DNA methylation plays an important role in the regulation of some biological processes. Up to now, with the development of machine learning models, there are several sequence-based deep learning models designed to predict DNA methylation states, whic...

Bagging and deep learning in optimal individualized treatment rules.

Biometrics
An ENsemble Deep Learning Optimal Treatment (EndLot) approach is proposed for personalized medicine problems. The statistical framework of the proposed method is based on the outcome weighted learning (OWL) framework which transforms the optimal deci...

Classification and Recognition of Ovarian Cells Based on Two-Dimensional Light Scattering Technology.

Journal of medical systems
Ovarian cancer is a very insidious malignant tumor. In order to detect ovarian cancer cells early, the classification and recognition of ovarian cancer cells is mainly studied by two-dimensional light scattering technology. Firstly, a single-cell two...

Convolutional neural network for cell classification using microscope images of intracellular actin networks.

PloS one
Automated cell classification is an important yet a challenging computer vision task with significant benefits to biomedicine. In recent years, there have been several studies attempted to build an artificial intelligence-based cell classifier using ...

Plasmonic MoO nanoparticles incorporated in Prussian blue frameworks exhibit highly efficient dual photothermal/photodynamic therapy.

Journal of materials chemistry. B
Development of near infrared (NIR) light-responsive nanomaterials for high performance multimodal phototherapy within a single nanoplatform is still challenging in technology and biomedicine. Herein, a new phototherapeutic nanoagent based on FDA-appr...

Time-dependent AI-Modeling of the anticancer efficacy of synthesized gallic acid analogues.

Computational biology and chemistry
BACKGROUND/AIM: Main objective of this study is mapping of the anticancer efficacy of synthesized gallic acid analogues using modeling and artificial intelligence (AI) over a large range of concentrations and exposure times to explore the underline m...

Objective risk stratification of prostate cancer using machine learning and radiomics applied to multiparametric magnetic resonance images.

Scientific reports
Multiparametric magnetic resonance imaging (mpMRI) has become increasingly important for the clinical assessment of prostate cancer (PCa), but its interpretation is generally variable due to its relatively subjective nature. Radiomics and classificat...

Predicting drug response of tumors from integrated genomic profiles by deep neural networks.

BMC medical genomics
BACKGROUND: The study of high-throughput genomic profiles from a pharmacogenomics viewpoint has provided unprecedented insights into the oncogenic features modulating drug response. A recent study screened for the response of a thousand human cancer ...