AIMC Topic: Cerebral Cortex

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Insights on the role of external globus pallidus in controlling absence seizures.

Neural networks : the official journal of the International Neural Network Society
Absence epilepsy, characterized by transient loss of awareness and bilaterally synchronous 2-4 Hz spike and wave discharges (SWDs) on electroencephalography (EEG) during absence seizures, is generally believed to arise from abnormal interactions betw...

Strong inhibitory signaling underlies stable temporal dynamics and working memory in spiking neural networks.

Nature neuroscience
Cortical neurons process information on multiple timescales, and areas important for working memory (WM) contain neurons capable of integrating information over a long timescale. However, the underlying mechanisms for the emergence of neuronal timesc...

Support vector machine-based classification of schizophrenia patients and healthy controls using structural magnetic resonance imaging from two independent sites.

PloS one
Structural brain alterations have been repeatedly reported in schizophrenia; however, the pathophysiology of its alterations remains unclear. Multivariate pattern recognition analysis such as support vector machines can classify patients and healthy ...

DNN-assisted statistical analysis of a model of local cortical circuits.

Scientific reports
In neuroscience, computational modeling is an effective way to gain insight into cortical mechanisms, yet the construction and analysis of large-scale network models-not to mention the extraction of underlying principles-are themselves challenging ta...

A Computational Model of the Brain Cortex and Its Synchronization.

BioMed research international
Obtaining the computational models for the functioning of the brain gives us a chance to understand the brain functionality thoroughly. This would help the development of better treatments for neurological illnesses and disorders. We created a cortic...

Predicting memory from study-related brain activity.

Journal of neurophysiology
To isolate brain activity that may reflect effective cognitive processes during the study phase of a memory task, cognitive neuroscientists commonly contrast brain activity during study of later-remembered versus later-forgotten items. This "subseque...

Predicting alcohol dependence from multi-site brain structural measures.

Human brain mapping
To identify neuroimaging biomarkers of alcohol dependence (AD) from structural magnetic resonance imaging, it may be useful to develop classification models that are explicitly generalizable to unseen sites and populations. This problem was explored ...

Reconstructing lost BOLD signal in individual participants using deep machine learning.

Nature communications
Signal loss in blood oxygen level-dependent (BOLD) functional neuroimaging is common and can lead to misinterpretation of findings. Here, we reconstructed compromised fMRI signal using deep machine learning. We trained a model to learn principles gov...

Identifying resting-state effective connectivity abnormalities in drug-naïve major depressive disorder diagnosis via graph convolutional networks.

Human brain mapping
Major depressive disorder (MDD) is a leading cause of disability; its symptoms interfere with social, occupational, interpersonal, and academic functioning. However, the diagnosis of MDD is still made by phenomenological approach. The advent of neuro...

Direct cortical thickness estimation using deep learning-based anatomy segmentation and cortex parcellation.

Human brain mapping
Accurate and reliable measures of cortical thickness from magnetic resonance imaging are an important biomarker to study neurodegenerative and neurological disorders. Diffeomorphic registration-based cortical thickness (DiReCT) is a known technique t...