AIMC Topic: Collagen

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Identification of a closed cutaneous injury after mechanical trauma caused by collision.

Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)
PURPOSE: Robotics has evolved rapidly in terms of mechanical design and control in the past few years. Collaborative robots that have direct contact with humans are being introduced in various fields, including industrial and medical services. Becaus...

The antifibrotic effect of isolate tagitinin C from tithonia diversifolia (Hemsley) A. Gray on keloid fibroblast cell.

The Pan African medical journal
INTRODUCTION: Keloids characterized by fibroblast hyperproliferation and depositions of collagen which similar to cancer cells. Tagitinin C is a class of sesquiterpene lactones (SLS) was isolated from the leaves of the moon flower (Hemsley) A. Gray....

Semi-supervised machine learning for automated species identification by collagen peptide mass fingerprinting.

BMC bioinformatics
BACKGROUND: Biomolecular methods for species identification are increasingly being utilised in the study of changing environments, both at the microscopic and macroscopic levels. High-throughput peptide mass fingerprinting has been largely applied to...

A deep learning approach to estimate chemically-treated collagenous tissue nonlinear anisotropic stress-strain responses from microscopy images.

Acta biomaterialia
UNLABELLED: Biological collagenous tissues comprised of networks of collagen fibers are suitable for a broad spectrum of medical applications owing to their attractive mechanical properties. In this study, we developed a noninvasive approach to estim...

A methodology for automated CPA extraction using liver biopsy image analysis and machine learning techniques.

Computer methods and programs in biomedicine
BACKGROUND AND OBJECTIVE: Collagen proportional area (CPA) extraction in liver biopsy images provides the degree of fibrosis expansion in liver tissue, which is the most characteristic histological alteration in hepatitis C virus (HCV). Assessment of...

Effect of actuating cell source on locomotion of organic living machines with electrocompacted collagen skeleton.

Bioinspiration & biomimetics
In robotics, there is a need for small scale, compliant actuators for use in medical applications or minimally invasive environmental monitoring. Biohybrid devices offer one solution to this need by using muscle cells to actuate compliant scaffolds. ...

Computationally Enabled Polychromatic Polarized Imaging Enables Mapping of Matrix Architectures that Promote Pancreatic Ductal Adenocarcinoma Dissemination.

The American journal of pathology
Pancreatic ductal adenocarcinoma (PDA) is a highly metastatic and lethal disease. In PDA, extracellular matrix (ECM) architectures, known as tumor-associated collagen signatures (TACSs), regulate invasion and metastatic spread in both early dissemina...

Interpretable deep learning method to predict wound healing progress based on collagen fibers in wound tissue.

Computers in biology and medicine
BACKGROUND AND OBJECTIVE: The dynamic evolution of collagen fibers during wound healing is crucial for assessing repair progression, guiding clinical treatment, and drug screening. Current quantitative methods analyzing collagen spatial patterns (den...

Machine learning-based label-free macrophage phenotyping in immune-material interactions.

Journal of materials chemistry. B
The rapid advancement of implantable biomedical materials necessitates a comprehensive understanding of macrophage interactions to optimize implant immunocompatibility. Macrophages, key immune regulators, exhibit phenotypic plasticity by polarizing i...