AIMC Topic: Collagen

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Effect of actuating cell source on locomotion of organic living machines with electrocompacted collagen skeleton.

Bioinspiration & biomimetics
In robotics, there is a need for small scale, compliant actuators for use in medical applications or minimally invasive environmental monitoring. Biohybrid devices offer one solution to this need by using muscle cells to actuate compliant scaffolds. ...

Sequence-driven species identification of ZooMS collagen peptide mass fingerprints.

Journal of proteomics
Developments in biomolecular species identification of animal tissues have been ongoing for decades, with collagen peptide mass fingerprinting becoming increasingly used in recent years. However, establishing confidence in the species biomarkers with...

Development of AI Based Fibrosis Detection Algorithm by SHG/TPEF Microscopy for Fully Quantified Liver Fibrosis Assessment in MASH.

Liver international : official journal of the International Association for the Study of the Liver
BACKGROUND AND AIMS: Metabolic dysfunction-associated steatotic liver disease (MASLD) is a major global cause of chronic liver disease, with the potential to progress from steatosis to metabolic dysfunction-associated steatohepatitis (MASH) and cirrh...

Effects of vascular endothelial cells on the neurite outgrowth of nerve cells.

Journal of bioscience and bioengineering
The vascular and neuronal networks are structurally complex and highly branched. These networks play an important role in supplying oxygen and sending signals to the tissues and organs in the body. This study proposes procedures to prepare in vitro n...

Antibacterial, Antifreezing, and Tough Electronic Skin Based on a Tanned Collagen Fiber Network for Underwater Grabber Application.

ACS applied materials & interfaces
The environment of underwater salvage is very special, and many factors such as real-time water conditions, the depth of salvage, and the complexity of underwater conditions could greatly affect the smooth progress of the salvage process. How to accu...

Computationally Enabled Polychromatic Polarized Imaging Enables Mapping of Matrix Architectures that Promote Pancreatic Ductal Adenocarcinoma Dissemination.

The American journal of pathology
Pancreatic ductal adenocarcinoma (PDA) is a highly metastatic and lethal disease. In PDA, extracellular matrix (ECM) architectures, known as tumor-associated collagen signatures (TACSs), regulate invasion and metastatic spread in both early dissemina...

Interpretable deep learning method to predict wound healing progress based on collagen fibers in wound tissue.

Computers in biology and medicine
BACKGROUND AND OBJECTIVE: The dynamic evolution of collagen fibers during wound healing is crucial for assessing repair progression, guiding clinical treatment, and drug screening. Current quantitative methods analyzing collagen spatial patterns (den...

Machine learning-based label-free macrophage phenotyping in immune-material interactions.

Journal of materials chemistry. B
The rapid advancement of implantable biomedical materials necessitates a comprehensive understanding of macrophage interactions to optimize implant immunocompatibility. Macrophages, key immune regulators, exhibit phenotypic plasticity by polarizing i...

Mesoscopic structural analysis via deep learning processing, with a special reference to in vitro alteration in collagen fibre induced by a gap junction inhibitor.

Microscopy (Oxford, England)
Dense connective tissue, including the ligament, tendon, fascia and cornea, is formed by regularly arranged collagen fibres synthesized by fibroblasts (Fbs). The mechanism by which fibre orientation is determined remains unclear. Periodontal ligament...

Tuning the Mechanical and Geometric Properties of Electrochemically Aligned Collagen Threads Toward Applications in Biohybrid Robotics.

Journal of biomechanical engineering
Electrochemically aligned collagen (ELAC) threads fabricated by the isoelectric focusing (IF) of collagen have previously shown potential in tissue engineering and more recently in the fabrication of biohybrid robot structures. For applications in bi...