MOTIVATION: Circular RNAs (circRNAs) are a new class of endogenous RNAs in animals and plants. During pre-RNA splicing, the 5' and 3' termini of exon(s) can be covalently ligated to form circRNAs through back-splicing (head-to-tail splicing). CircRNA...
Reliable detection of disseminated tumor cells and of the biodistribution of tumor-targeting therapeutic antibodies within the entire body has long been needed to better understand and treat cancer metastasis. Here, we developed an integrated pipelin...
A major challenge in cancer treatment is predicting clinical response to anti-cancer drugs on a personalized basis. Using a pharmacogenomics database of 1,001 cancer cell lines, we trained deep neural networks for prediction of drug response and asse...
The outstanding performance of deep learning (DL) for computer vision and natural language processing has fueled increased interest in applying these algorithms more broadly in both research and practice. This study investigates the application of DL...
Clinical and translational gastroenterology
Dec 1, 2019
OBJECTIVES: Application of artificial intelligence in gastrointestinal endoscopy is increasing. The aim of the study was to examine the accuracy of convolutional neural network (CNN) using endoscopic images for evaluating Helicobacter pylori (H. pylo...
PURPOSE: Computed tomography for the reconstruction of region of interest (ROI) has advantages in reducing the x-ray dose and the use of a small detector. However, standard analytic reconstruction methods such as filtered back projection (FBP) suffer...
PURPOSE: Metal artifact is a quite common problem in diagnostic dental computed tomography (CT) images. Due to the high attenuation of heavy materials such as metal, severe global artifacts can occur in reconstructions. Typical metal artifact reducti...
Machine Learning, especially deep learning, has been used in typical x-ray computed tomography (CT) applications, including image reconstruction, image enhancement, image domain feature detection and image domain feature characterization. To our know...
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