International journal of methods in psychiatric research
Feb 5, 2020
OBJECTIVE: Schizophrenia is a chronic and debilitating neuropsychiatric disorder. It has been suggested that impaired brain connectivity underlies the pathophysiology of schizophrenia. Network analysis has thus recently emerged in the field of schizo...
Schizophrenia is a severe psychiatric disorder associated with both structural and functional brain abnormalities. In the past few years, there has been growing interest in the application of machine learning techniques to neuroimaging data for the d...
PURPOSE: Medical image synthesis can simulate a target modality of interest based on existing modalities and has the potential to save scanning time while contributing to efficient data collection. This study proposed a three-dimensional (3D) deep le...
While the major white matter tracts are of great interest to numerous studies in neuroscience and medicine, their manual dissection in larger cohorts from diffusion MRI tractograms is time-consuming, requires expert knowledge and is hard to reproduce...
OBJECTIVE: Vagus nerve stimulation (VNS) is a common treatment for medically intractable epilepsy, but response rates are highly variable, with no preoperative means of identifying good candidates. This study aimed to predict VNS response using struc...
Patients with cerebral small vessel disease (SVD) frequently show decline in cognitive performance. However, neuroimaging in SVD patients discloses a wide range of brain lesions and alterations so that it is often difficult to understand which of the...
International journal of radiation oncology, biology, physics
Jul 22, 2019
PURPOSE: A noninvasive diagnostic method to predict the degree of malignancy accurately would be of great help in glioma management. This study aimed to create a highly accurate machine learning model to perform glioma grading.
PURPOSE: Diffusion-weighted magnetic resonance imaging (DW-MRI) is of critical importance for characterizing in-vivo white matter. Models relating microarchitecture to observed DW-MRI signals as a function of diffusion sensitization are the lens thro...
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
Jul 11, 2019
PURPOSE: Glioblastoma is routinely treated by concomitant radiochemotherapy. Current target definition guidelines use anatomic MRI (magnetic resonance imaging) scans, taking into account contrast enhancement and the rather unspecific hyperintensity o...
PURPOSE: Adolescent major depressive disorder (MDD) is a highly prevalent, incapacitating and costly illness. Many depressed teens do not improve with cognitive behavioral therapy (CBT), a first-line treatment for adolescent MDD, and face devastating...