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Double-Blind Method

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Use of Topical Lidocaine Gel Plus Paracervical Blockade vs. Paracervical Blockade Alone for Pain Management During Manual Vacuum Aspiration: ADouble-Blind, Randomized, Placebo-Controlled Trial.

Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC
OBJECTIVE: To evaluate if the use of lidocaine gel applied to the cervix prior to manual vacuum aspiration (MVA) in addition to paracervical blockade is useful in reducing the level of pain associated with the procedure.

Dexamethasone Versus Ketamine in the Interscalene Block in Patients Undergoing Arthroscopic Shoulder Surgery: A Randomized Double-Blinded Study.

Asian journal of anesthesiology
OBJECTIVE: Arthroscopic shoulder surgery (ASS) is often followed by severe pain. Interscalene brachial plexus block (ISB) was used to relieve such pain. The aim of the study was to compare the effect of adding either dexamethasone or ketamine to ISB ...

Cocoa flavanol effects on markers of oxidative stress and recovery after muscle damage protocol in elite rugby players.

Nutrition (Burbank, Los Angeles County, Calif.)
OBJECTIVES: Strenuous exercise can impair athletic performance due to muscular inflammation and oxidative stress. Antioxidants such as cocoa flavanols have been used as a supplement to prevent oxidative stress; however, the benefits of dietary antiox...

Local Infiltration Analgesia With Liposomal Bupivacaine Improves Early Outcomes After Total Knee Arthroplasty: 24-Hour Data From the PILLAR Study.

The Journal of arthroplasty
BACKGROUND: Enhanced postoperative care pathways have shifted total knee arthroplasty (TKA) to outpatient and short-stay settings, placing greater emphasis on predischarge outcomes. In this study, we report prespecified secondary and tertiary end poi...

Perceptual Effects of Adjusting Hearing-Aid Gain by Means of a Machine-Learning Approach Based on Individual User Preference.

Trends in hearing
This study investigated a method to adjust hearing-aid gain by use of a machine-learning algorithm that estimates the optimal setting of gain parameters based on user preference indicated in an iterative paired-comparison procedure. Twenty hearing-im...

Using Artificial Intelligence to Identify Factors Associated with Autism Spectrum Disorder in Adolescents with Cerebral Palsy.

Neuropediatrics
Autism spectrum disorder (ASD) is common in adolescents with cerebral palsy (CP) and there is a lack of studies applying artificial intelligence to investigate this field and this population in particular. The aim of this study is to develop and test...

Influence of New Technologies on Post-Stroke Rehabilitation: A Comparison of Armeo Spring to the Kinect System.

Medicina (Kaunas, Lithuania)
BACKGROUND: New technologies to improve post-stroke rehabilitation outcomes are of great interest and have a positive impact on functional, motor, and cognitive recovery. Identifying the most effective rehabilitation intervention is a recognized prio...

A Radical Proposition: Opioid-sparing Prostatectomy.

European urology focus
Radical prostatectomy has largely become a procedure requiring a single day in the hospital with improving convalescence. Pre-operative counseling on perioperatively expectations including a discussion of pain management using non-opioid alternatives...

Machine Learning Identifies Large-Scale Reward-Related Activity Modulated by Dopaminergic Enhancement in Major Depression.

Biological psychiatry. Cognitive neuroscience and neuroimaging
BACKGROUND: Theoretical models have emphasized systems-level abnormalities in major depressive disorder (MDD). For unbiased yet rigorous evaluations of pathophysiological mechanisms underlying MDD, it is critically important to develop data-driven ap...

Machine Learning Prediction of Mortality and Hospitalization in Heart Failure With Preserved Ejection Fraction.

JACC. Heart failure
OBJECTIVES: This study sought to develop models for predicting mortality and heart failure (HF) hospitalization for outpatients with HF with preserved ejection fraction (HFpEF) in the TOPCAT (Treatment of Preserved Cardiac Function Heart Failure with...