AIMC Topic: Female

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Single-cell RNA sequencing identifies CD8Teff cell activation as a predictive biomarker in triple-negative breast cancer immunotherapy.

Molecular biomedicine
Immunotherapy has emerged as a promising treatment option for triple-negative breast cancer (TNBC); however, the pronounced heterogeneity of the tumor immune microenvironment significantly hinders the prediction of therapeutic efficacy, with effectiv...

Enteral versus parenteral nutrition in auto-HCT: a randomized controlled trial on clinical outcomes and gut microbiome dynamics.

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer
Disruption of the gut microbiome is a common consequence of chemotherapy, linked with detrimental treatment outcomes (e.g. sepsis), especially in haematopoietic stem cell transplant (HCT) recipients. Preclinical data suggest that enteral nutrition (E...

Performance of an artificial intelligence algorithm for interpreting lung sounds from children hospitalised with pneumonia in Malawi.

Journal of global health
BACKGROUND: Pneumonia is a leading cause of death in under five year olds globally. World Health Organization (WHO) pneumonia diagnostic guidelines rely on non-specific clinical findings. Lung auscultation could improve pneumonia diagnosis, but conve...

Mortality prediction for ICU patients with mental disorders using large language models ensemble and unstructured medical notes.

PloS one
Assessing mortality risk in the intensive care unit (ICU) is crucial for improving clinical outcomes and management strategies. Conventional artificial intelligence studies often neglect vital clinical information contained in unstructured medical no...

Risk prediction of all-cause mortality in hospitalized patients with severe acute pancreatitis by serum urea nitrogen/albumin ratio.

PloS one
BACKGROUND: Classification of risk levels in patients with acute pancreatitis remains a difficult task. Although some biomarkers have emerged to predict the prognosis of patients with acute pancreatitis, they have not been widely used in clinical pra...

Development and validation of a machine learning-based predictive model for clinical remission in Crohn's disease patients receiving Adalimumab therapy.

PloS one
Crohn's disease (CD), a chronic inflammatory bowel disease, is witnessing a rising global incidence. Adalimumab (ADA), a biological agent, is widely used in its treatment. However, patients exhibit significant individual variability in responses to A...

Optimized deep learning-accelerated single-breath-hold abdominal HASTE with and without fat saturation improves and accelerates abdominal imaging at 3 Tesla.

BMC medical imaging
BACKGROUND: Deep learning-accelerated single-shot turbo-spin-echo techniques (DL-HASTE) enable single-breath-hold T2-weighted abdominal imaging. However, studies evaluating the image quality of DL-HASTE with and without fat saturation (FS) remain lim...

Large Language Models' Clinical Decision-Making on When to Perform a Kidney Biopsy: Comparative Study.

Journal of medical Internet research
BACKGROUND: Artificial intelligence (AI) and large language models (LLMs) are increasing in sophistication and are being integrated into many disciplines. The potential for LLMs to augment clinical decision-making is an evolving area of research.

Fusion of X-Ray Images and Clinical Data for a Multimodal Deep Learning Prediction Model of Osteoporosis: Algorithm Development and Validation Study.

JMIR medical informatics
BACKGROUND: Osteoporosis is a bone disease characterized by reduced bone mineral density and mass, which increase the risk of fragility fractures in patients. Artificial intelligence can mine imaging features specific to different bone densities, sha...

Predicting Surgical Site Infection after Lumbar Laminectomy and Discectomy: A Cutting-edge Algorithmic Approach by Incorporating Ensembled Stacking into the Current State-of-the-art for Automated Machine Learning.

Neurosurgical review
To develop an algorithmic approach for predicting surgical site infections (SSIs) in patients undergoing lumbar laminectomy and discectomy for adult degenerative spinal disease (DSD) by incorporating ensembled stacking into state-of-the-art (SOTA) au...