MOTIVATION: Enabling clinicians and researchers to directly interact with global genomic data resources by removing technological barriers is vital for medical genomics. AskBeacon enables large language models (LLMs) to be applied to securely shared ...
Translational vision science & technology
Mar 3, 2025
PURPOSE: The purpose of this study was to develop models that predict which patients with glaucoma will progress to require surgery, combining structured data from electronic health records (EHRs) and retinal fiber layer optical coherence tomography ...
Investigative ophthalmology & visual science
Mar 3, 2025
PURPOSE: This study aimed to elucidate whether machine learning algorithms applied to vitreous levels of immune mediators predict the diagnosis of 12 representative intraocular diseases, and identify immune mediators driving the predictive power of m...
Clinical trials are fundamental to evidence-based medicine, providing patients with access to novel therapeutics and advancing scientific knowledge. However, patient comprehension of trial information remains a critical challenge, as registries like ...
Investigative ophthalmology & visual science
Mar 3, 2025
PURPOSE: The purpose of this study was to define structure-function correlation of geographic atrophy (GA) on optical coherence tomography (OCT) and functional testing on microperimetry (MP) based on deep-learning (DL)-quantified spectral-domain OCT ...
Investigative ophthalmology & visual science
Mar 3, 2025
PURPOSE: Loss of retinal perfusion is associated with both onset and worsening of diabetic retinopathy (DR). Optical coherence tomography angiography is a noninvasive method for measuring the nonperfusion area (NPA) and has promise as a scalable scre...
BACKGROUND: Adequate patient awareness and understanding of cancer clinical trials is essential for trial recruitment, informed decision making, and protocol adherence. Although large language models (LLMs) have shown promise for patient education, t...
European heart journal. Cardiovascular Imaging
Mar 3, 2025
AIMS: Identification of proximal coronary artery calcium (CAC) may improve prediction of major adverse cardiac events (MACE) beyond the CAC score, particularly in patients with low CAC burden. We investigated whether the proximal CAC can be detected ...
BACKGROUND AND AIMS: Artificial intelligence (AI) algorithms in 12-lead electrocardiogram (ECG) provides promising age prediction methods. This study investigated whether the discrepancy between ECG-derived AI-predicted age (AI-ECG age) and chronolog...
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