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Decoding pan-cancer treatment outcomes using multimodal real-world data and explainable artificial intelligence.

Nature cancer
Despite advances in precision oncology, clinical decision-making still relies on limited variables and expert knowledge. To address this limitation, we combined multimodal real-world data and explainable artificial intelligence (xAI) to introduce AI-...

Operational Advantages of Novel Strategies Supported by Portability and Artificial Intelligence for Breast Cancer Screening in Low-Resource Rural Areas: Opportunities to Address Health Inequities and Vulnerability.

Medicina (Kaunas, Lithuania)
Early detection of breast cancer plays a crucial role in reducing the number of cases diagnosed at advanced stages, thereby lowering the high healthcare costs required to achieve disease-free survival and helping to prevent avoidable premature deaths...

Postoperative fever following surgery for oral cancer: Incidence, risk factors, and the formulation of a machine learning-based predictive model.

BMC oral health
BACKGROUND: Postoperative fever (POF) is a common occurrence in patients undergoing major surgery, presenting challenges and burdens for both patients and surgeons yet. This study endeavors to examine the incidence, identify risk factors, and establi...

Risk factors and machine learning prediction models for intrahepatic cholestasis of pregnancy.

BMC pregnancy and childbirth
BACKGROUND: Intrahepatic cholestasis of pregnancy (ICP) is a liver disorder that occurs in the second and third trimesters of pregnancy and is associated with a significant risk of fetal complications, including premature birth and fetal death. In cl...

Enhancing individual glomerular filtration rate assessment: can we trust the equation? Development and validation of machine learning models to assess the trustworthiness of estimated GFR compared to measured GFR.

BMC nephrology
BACKGROUND: Creatinine-based estimated glomerular filtration rate (eGFR) equations are widely used in clinical practice but exhibit inherent limitations. On the other side, measuring GFR is time consuming and not available in routine clinical practic...

Integrating multiomics analysis and machine learning to refine the molecular subtyping and prognostic analysis of stomach adenocarcinoma.

Scientific reports
Stomach adenocarcinoma (STAD) is a common malignancy with high heterogeneity and a lack of highly precise treatment options. We downloaded the multiomics data of STAD patients in The Cancer Genome Atlas (TCGA)-STAD cohort, which included mRNA, microR...

Risk factor assessment of prediabetes and diabetes based on epidemic characteristics in new urban areas: a retrospective and a machine learning study.

Scientific reports
To explore in depth the characteristics of the risk factors for diabetes and prediabetes pathogenesis and progression in special regions. We investigated medical data from 160 thousand cases in the newly developing urban area of a large modern city f...

Applying YOLOv6 as an ensemble federated learning framework to classify breast cancer pathology images.

Scientific reports
The most common carcinoma-related cause of death among women is breast cancer. Early detection is crucial, and the manual screening method may lead to a delayed diagnosis, which would delay treatment and put lives at risk. Mammography imaging is advi...

Improving explainability of post-separation suicide attempt prediction models for transitioning service members: insights from the Army Study to Assess Risk and Resilience in Servicemembers - Longitudinal Study.

Translational psychiatry
Risk of U.S. Army soldier suicide-related behaviors increases substantially after separation from service. As universal prevention programs have been unable to resolve this problem, a previously reported machine learning model was developed using pre...