AIMC Topic: Fibrinolytic Agents
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Bioinspired Soft Microrobots with Precise Magneto-Collective Control for Microvascular Thrombolysis.
Advanced materials (Deerfield Beach, Fla.)
May 20, 2020
New-era soft microrobots for biomedical applications need to mimic the essential structures and collective functions of creatures from nature. Biocompatible interfaces, intelligent functionalities, and precise locomotion control in a collective manne...
Can clinical audits be enhanced by pathway simulation and machine learning? An example from the acute stroke pathway.
BMJ open
Sep 17, 2019
OBJECTIVE: To evaluate the application of clinical pathway simulation in machine learning, using clinical audit data, in order to identify key drivers for improving use and speed of thrombolysis at individual hospitals.
Telemedicine, Telestroke, and Artificial Intelligence Can Be Coded with the International Classification of Health Interventions.
Telemedicine journal and e-health : the official journal of the American Telemedicine Association
Jul 16, 2019
Machine learning methods for leveraging baseline covariate information to improve the efficiency of clinical trials.
Statistics in medicine
Nov 25, 2018
Clinical trials are widely considered the gold standard for treatment evaluation, and they can be highly expensive in terms of time and money. The efficiency of clinical trials can be improved by incorporating information from baseline covariates tha...
Prediction of Tissue Outcome and Assessment of Treatment Effect in Acute Ischemic Stroke Using Deep Learning.
Stroke
May 2, 2018
BACKGROUND AND PURPOSE: Treatment options for patients with acute ischemic stroke depend on the volume of salvageable tissue. This volume assessment is currently based on fixed thresholds and single imagine modalities, limiting accuracy. We wish to d...
Antiproliferative and anti-apoptotic effect of astaxanthin in an oxygen-induced retinopathy mouse model.
Canadian journal of ophthalmology. Journal canadien d'ophtalmologie
Apr 11, 2018
OBJECTIVE: To evaluate the impact of intravitreal (IV) and intraperitoneal (IP) astaxanthin (AST) injections on neovascular development (ND), retinal morphology, and apoptotic activity in a C57BL/6J mouse model with hyperoxia-induced retinopathy (HIR...
Applying natural language processing techniques to develop a task-specific EMR interface for timely stroke thrombolysis: A feasibility study.
International journal of medical informatics
Feb 8, 2018
OBJECTIVE: To reduce errors in determining eligibility for intravenous thrombolytic therapy (IVT) in stroke patients through use of an enhanced task-specific electronic medical record (EMR) interface powered by natural language processing (NLP) techn...
Changes in glomerular filtration rate and outcomes in patients with atrial fibrillation.
American heart journal
Dec 30, 2017
BACKGROUND: Patients with kidney disease are more likely to develop atrial fibrillation (AF) than individuals with normal renal function, and more likely to suffer ischemic stroke (IS)/thromboembolism (TE). We investigated the relationship of kidney ...
Aged, 80 and over
Male
Middle Aged
Follow-Up Studies
Risk Assessment
Humans
Drug Therapy, Combination
Fibrinolytic Agents
Disease Progression
Comorbidity
Anti-Arrhythmia Agents
Retrospective Studies
Confidence Intervals
Severity of Illness Index
Atrial Fibrillation
Female
Renal Insufficiency
Cohort Studies
Survival Analysis
Proportional Hazards Models
Aged
Treatment Outcome
Glomerular Filtration Rate
Spontaneous Intraventricular Hemorrhage: When Should Intraventricular tPA Be Considered?
Seminars in respiratory and critical care medicine
Dec 20, 2017
Spontaneous intracerebral hemorrhage (ICH) is the most common cause of intraventricular hemorrhage (IVH) in adults. Complicating approximately 40% of ICH cases, IVH adds to the morbidity and mortality of this often fatal form of stroke. It is also a ...
Pneumatic Displacement of Submacular Hemorrhage with Subretinal Air and Tissue Plasminogen Activator: Initial United States Experience.
Ophthalmology. Retina
Sep 28, 2017
PURPOSE: To present the initial multicenter experience of using subretinal air injection in combination with tissue plasminogen activator (tPA) at the time of pars plana vitrectomy (PPV) to displace submacular hemorrhage (SMH).
Male
Middle Aged
Time Factors
United States
Treatment Outcome
Fluorescein Angiography
Follow-Up Studies
Humans
Retina
Injections, Intraocular
Retrospective Studies
Tissue Plasminogen Activator
Visual Acuity
Retinal Hemorrhage
Female
Air
Fibrinolytic Agents
Vitrectomy
Endotamponade
Aged
Tomography, Optical Coherence
Aged, 80 and over
Fundus Oculi
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