Fatty acid metabolism is critically involved in glioblastoma (GBM) pathogenesis; however, its regulatory mechanisms remain incompletely understood. In this study, we identified biliverdin reductase A (BLVRA) as a novel metabolic driver and prognostic...
Glioblastoma is an aggressive, malignant primary brain tumour and the most prevalent histological type of glioma. Our study attempted to investigate the independent predictors of overall survival (OS) and cancer-specific survival (CSS) in Asian patie...
Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society
Aug 7, 2025
OBJECTIVE: Glioblastoma (GBM) is the most aggressive malignant brain tumor, associated with poor prognosis and limited therapeutic options. Accurate prognostic modeling is essential for guiding personalized treatment strategies. However, existing mod...
Glioblastoma multiforme (GBM) is the most aggressive type of brain cancer, making effective treatments essential to improve patient survival. To advance the understanding of GBM and develop more effective therapies, preclinical studies commonly use m...
Assessing MGMT promoter methylation is crucial for determining appropriate glioblastoma therapy. Previous studies have focused on intratumoral regions, overlooking the peritumoral area. This study aimed to develop a radiomic model using MRI-derived f...
Raman spectroscopy provides comprehensive biochemical information on a sample's composition, yet it is often used to analyze aggregated spectra rather than specific shifts. We introduce Fluorescence Guided Raman Spectroscopy (FGRS) as a methodology e...
Tumor suppressor genes (TSGs) are critical regulators of cellular homeostasis and are extensively studied in cancer biology. However, their roles in neurodegenerative diseases, particularly Alzheimer's disease (AD), remain poorly understood. Recent e...
Brain tumors, particularly glioblastoma multiforme, are considered one of the most threatening types of tumors in neuro-oncology. Segmenting brain tumors is a crucial part of medical imaging. It plays a key role in diagnosing conditions, planning tre...
Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society
Jun 9, 2025
Accurately predicting glioblastoma (GBM) recurrence is crucial for guiding the planning of target areas in subsequent radiotherapy and radiosurgery for glioma patients. Current prediction methods can determine the likelihood and type of recurrence bu...
Glioblastoma (GBM) is classified into subtypes according to the molecular expression profile; the proneural subtype has a relatively good prognosis, and the mesenchymal type is the most aggressive form with the worst prognosis. GBM undergoes proneura...
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