BACKGROUND: Fusion of multi-modal data can improve the performance of deep learning models. However, missing modalities are common in medical data due to patient specificity, which is detrimental to the performance of multi-modal models in applicatio...
BACKGROUND: The global mental health crisis has created barriers to youth mental healthcare, leaving many disorders unaddressed. Precision prevention, which identifies individual risks, offers the potential for tailored interventions. While natural l...
BACKGROUND: The stroke risk in patients with subclinical atrial fibrillation (AF) is underestimated. By identifying patients at high risk of embolic stroke, health-care professionals can make more informed decisions regarding anticoagulation treatmen...
Current opinion in structural biology
Feb 21, 2025
Large Language Models for proteins, namely protein Language Models (pLMs), have begun to provide an important alternative to capturing the information encoded in a protein sequence in computers. Arguably, pLMs have advanced importantly to understandi...
Journal of applied clinical medical physics
Feb 21, 2025
OBJECTIVE: To develop and validate a HyperArc-based RapidPlan (HARP) model for three-fraction brain stereotactic radiotherapy (SRT) plans to then use to replan previously treated five-fraction SRT plans. Demonstrating the possibility of reducing the ...
Hepatitis C virus (HCV) infection represents a significant contributor to chronic liver disease on a global scale. The prompt identification and management of HCV are imperative in order to avert complications and to maintain control over the disease...
DNA methylation (DNAm) is a key epigenetic mark with essential roles in gene regulation, mammalian development, and human diseases. Single-cell technologies enable profiling DNAm at cytosines in individual cells, but they often suffer from low covera...
Neuromorphic electronics are inspired by the human brain's compact, energy-efficient nature and its parallel-processing capabilities. Beyond the brain, the entire human nervous system, with its hierarchical structure, efficiently preprocesses complex...
The case-control study is a widely used method for investigating the genetic underpinnings of binary traits. However, long-term, prospective cohort studies often grapple with absent or evolving health-related outcomes. Here, we propose two methods, l...
BACKGROUND: The abnormalities in brain functional connectivity (FC) and graph topology (GT) in patients with schizophrenia (SZ) are unclear. Researchers proposed machine learning algorithms by combining FC or GT to identify SZ from healthy controls. ...
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