BACKGROUND: Adaptive radiotherapy (ART) is an advanced form of image-guided radiotherapy that involves the re-contouring and re-planning of a patient's treatment plan, either while the patient is on the table (online) or in between fractions (offline...
Lactylation is a post-translational modification that can influence the onset and progression of various diseases.However, its role in Idiopathic Pulmonary Fibrosis (IPF) has not been systematically investigated. Single-cell sequencing and bulk RNA s...
Chemical communications (Cambridge, England)
Nov 20, 2025
Optical biosensors have emerged as a transformative class of point-of-care diagnostic (POCD) devices, offering sensitive, specific, and rapid detection of diseases. The integration of optical biosensors with artificial intelligence (AI) brings a new ...
Gastric cancer (GC) remains one of the most prevalent and lethal malignancies worldwide, necessitating the development of efficient, non-invasive methods for early detection. In this study, a serum diagnostic approach based on shell-isolated nanopart...
Injury prevention : journal of the International Society for Child and Adolescent Injury Prevention
Nov 20, 2025
INTRODUCTION: Road traffic injuries (RTIs) rank among the top causes of mortality and disability in children and adolescents, resulting in substantial socioeconomic impacts.
BACKGROUND: Machine learning shows great potential in science but struggles with complex, high-dimensional multi-omics data. PD progression is long, diagnosed mainly by clinical signs. This paper proposes a novel decision fusion method to improve the...
Urban air pollution poses a significant threat to public health and urban sustainability in megacities like Paris. We cast forecasting as a short-term, next-hour prediction task for PM2.5, NO, and CO, using hourly meteorology and recent pollutant his...
BACKGROUND: Acute Respiratory Distress Syndrome (ARDS) remains a critical condition associated with high mortality rates, prolonged hospitalization, and reduced quality of life despite advances in critical care. The albumin-corrected anion gap (ACAG)...
Homologous recombination deficiency (HRD) is a critical biomarker for guiding targeted therapies, yet the full range of somatic alterations driving HRD across cancers remains incompletely characterized. Here, we present a tumor-agnostic machine learn...
Recently, the severe side effects related to the widespread consumption of antidepressants (ADs) have alarmingly created a global challenge for clinics and forensic laboratories. This study introduces a machine learning-empowered multicolor fluoresce...
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