AIMC Topic: Humans

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Ethical challenges in biomarker research and precision medicine - a qualitative study in dermatology.

BMC medical ethics
BACKGROUND: Over 300 million individuals worldwide live with Atopic Dermatitis and Psoriasis, which are among the most common chronic inflammatory skin diseases. Multimodal biomarkers are currently being developed using large-scale data and artificia...

Relationship between C-reactive protein triglyceride glucose index and cardiovascular disease risk: a cross-sectional analysis with machine learning.

BMC medical informatics and decision making
BACKGROUND: Cardiovascular disease (CVD) continues to be a leading cause of disease burden and mortality worldwide. Identifying reliable biomarkers for CVD risk assessment is essential. This study investigates the association between the C-reactive p...

Configuration design of ankle rehabilitation robots: a systematic review and future prospects.

Journal of neuroengineering and rehabilitation
Compared to traditional therapist-assisted rehabilitation training, ankle rehabilitation robots (ARRs) can offer a wider variety of active and passive training strategies for stroke and fracture patients. This enhances patient recovery outcomes and e...

Distinct immune-metabolic phenotypes underlie poor coronary collateral circulation.

Cardiovascular diabetology
BACKGROUND: Coronary collateral circulation (CCC) significantly impacts myocardial perfusion and clinical outcomes in coronary artery disease patients, yet the underlying molecular heterogeneity remains inadequately characterized.

Unveiling the burden of snakebite injuries: an EQ-5D-5 L-based evaluation of health-related quality of life.

BMC public health
BACKGROUND: Snakebite envenoming remains poorly understood in terms of long-term health-related quality of life (HRQoL), particularly in China where standardized assessments are lacking. This study is the first to comprehensively evaluate HRQoL impai...

Anxiety responses and testing intentions among gay and bisexual men using an AI-powered HIV/STI risk assessment tool: a quasi-experimental study.

BMC public health
INTRODUCTION: Web-based tools for the assessment of the risk of sexually transmitted infections (STI) may increase testing but also may induce anxiety. We evaluated anxiety responses and testing intentions among gay, bisexual and other men who have s...

XGBoost-based analysis of maternal and biochemical factors associated with spontaneous preterm birth: a retrospective cohort study.

BMC pregnancy and childbirth
BACKGROUND: Spontaneous preterm birth (sPTB) remains a major cause of neonatal morbidity and early risk assessment was poor. This study aimed to evaluate the association and predictive potential of serum biomarkers and maternal factors with sPTB.

Impact of contrast enhancement boost and super-resolution deep learning reconstruction on pediatric congenital heart disease CTA scans: ultra-low contrast dose.

BMC medical imaging
OBJECTIVE: To evaluate the feasibility of using contrast enhancement boost (CE-Boost) combined with super-resolution deep learning reconstruction (SR-DLR) to reduce contrast agent dosage in pediatric patients with congenital heart disease (CHD).

Talk2Biomodels: AI agent-based open-source LLM initiative for kinetic biological models.

BMC bioinformatics
BACKGROUND: Quantitative kinetic models of biological regulatory processes play an important role in understanding disease mechanisms. However, their simulation and analysis require specialized domain expertise.

scMFF: a machine learning framework with multiple feature fusion strategies for cell type identification.

BMC bioinformatics
Accurate cell type classification is critical for downstream analysis in single-cell RNA sequencing (scRNA-seq). Most existing methods rely on a single type of feature representation-such as statistical, information theory, matrix factorization, or d...