AIMC Topic: Humans

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The role of endothelial cell-related gene COL1A1 in prostate cancer diagnosis and immunotherapy: insights from machine learning and single-cell analysis.

Biology direct
BACKGROUND: Endothelial cells are integral components of the tumor microenvironment and play a multifaceted role in tumor immunotherapy. Targeting endothelial cells and related signaling pathways can improve the effectiveness of immunotherapy by norm...

A machine learning model and identification of immune infiltration for chronic obstructive pulmonary disease based on disulfidptosis-related genes.

BMC medical genomics
BACKGROUND: Chronic obstructive pulmonary disease (COPD) is a chronic and progressive lung disease. Disulfidptosis-related genes (DRGs) may be involved in the pathogenesis of COPD. From the perspective of predictive, preventive, and personalized medi...

Early childhood caries risk prediction using machine learning approaches in Bangladesh.

BMC oral health
BACKGROUND: In the last years, artificial intelligence (AI) has contributed to improving healthcare including dentistry. The objective of this study was to develop a machine learning (ML) model for early childhood caries (ECC) prediction by identifyi...

Feasibility of occlusal plane in predicting the changes in anteroposterior mandibular position: a comprehensive analysis using deep learning-based three-dimensional models.

BMC oral health
BACKGROUND: A comprehensive analysis of the occlusal plane (OP) inclination in predicting anteroposterior mandibular position (APMP) changes is still lacking. This study aimed to analyse the relationships between inclinations of different OPs and APM...

Hybrid natural language processing tool for semantic annotation of medical texts in Spanish.

BMC bioinformatics
BACKGROUND: Natural language processing (NLP) enables the extraction of information embedded within unstructured texts, such as clinical case reports and trial eligibility criteria. By identifying relevant medical concepts, NLP facilitates the genera...

Exploring artificial intelligence for differentiating early syphilis from other skin lesions: a pilot study.

BMC infectious diseases
BACKGROUND: Early diagnosis of syphilis is vital for its effective control. This study aimed to develop an Artificial Intelligence (AI) diagnostic model based on radiomics technology to distinguish early syphilis from other clinical skin lesions.

Effective BCDNet-based breast cancer classification model using hybrid deep learning with VGG16-based optimal feature extraction.

BMC medical imaging
PROBLEM: Breast cancer is a leading cause of death among women, and early detection is crucial for improving survival rates. The manual breast cancer diagnosis utilizes more time and is subjective. Also, the previous CAD models mostly depend on manma...

Clustering-based binary Grey Wolf Optimisation model with 6LDCNNet for prediction of heart disease using patient data.

Scientific reports
In recent years, the healthcare data system has expanded rapidly, allowing for the identification of important health trends and facilitating targeted preventative care. Heart disease remains a leading cause of death in developed countries, often lea...

Attention-based deep learning for accurate cell image analysis.

Scientific reports
High-content analysis (HCA) holds enormous potential for drug discovery and research, but widely used methods can be cumbersome and yield inaccurate results. Noisy and redundant signals in cell images impede accurate deep learning-based image analysi...