Talk and Deteriorate refers to a clinical course where a patient is able to speak immediately after a traumatic brain injury but subsequently deteriorates in consciousness. Talk and Deteriorate outcomes are poor, and reliable prediction may help impr...
International journal of pharmaceutics
Oct 10, 2025
Non-clinical laboratories are under increasing regulatory pressure from agencies such as the FDA, EMA, and MHRA to ensure data integrity, traceability, and compliance with Good Laboratory Practice (GLP) and Good Documentation Practice (GDP). While Ar...
BACKGROUND: Spinal angiography (SA) remains the gold standard for evaluating spinal cord vasculature, but traditional approaches expose operators and patients to significant ionizing radiation. Robotic-assisted platforms offer potential advantages th...
Understanding vaccine hesitancy is a critical public health challenge, yet traditional statistical methods often fail to capture the complex drivers behind it. This study uses COVID-19 vaccine hesitancy in a rural population as a case study to demons...
BACKGROUND AND OBJECTIVES: Over half of all deaths after traumatic brain injury (TBI) follow the decision to withdraw life-sustaining therapy (WLST). Despite recent improvements in TBI mortality, rates of WLST have remained unchanged, potentially ref...
Journal of chemical information and modeling
Oct 10, 2025
Phosphorylation dynamically orchestrates the protein-protein interaction (PPI) network that governs cellular signaling, and its dysregulation frequently drives malignant transformation and neurodegeneration. We present PhosPPI-SEQ, an interpretable d...
Journal of chemical information and modeling
Oct 10, 2025
Effective anticancer drug combinations are crucial for advancing cancer treatment, yet predicting drug synergy remains challenging due to the complexity of biological interactions. Existing methods struggle to integrate multimodal features and to mod...
Skin thermophysical properties are key for health assessment with real-time monitoring enabling early detection of skin-related issues. A polydimethylsiloxane-encapsulated Peano fractal conformal sensor is fabricated by flexible printed circuit techn...
Aldehyde compounds are significantly associated with diabetes mellitus. The metabolic profile of aldehydes can enhance understanding of the mechanisms underlying development of diabetes. This study employed a pair of stable isotope labeling (SIL) rea...
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