AIMC Topic: Humans

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Identification of key genes as diagnostic biomarkers for IBD using bioinformatics and machine learning.

Journal of translational medicine
BACKGROUND: The pathogenesis of inflammatory bowel disease (IBD) involves complex molecular mechanisms, and achieving clinical remission remains challenging. This study aims to identify IBD-potential biomarkers, analyze their correlation with immune ...

The value of triglyceride-glucose index-related indices in evaluating migraine: perspectives from multi-centre cross-sectional studies and machine learning models.

Lipids in health and disease
BACKGROUND: This study employed representative data from the U.S. and China to delve into the correlation among migraine prevalence, the triglyceride‒glucose index, a marker of insulin resistance, and the composite indicator of obesity.

Keyword-optimized template insertion for clinical note classification via prompt-based learning.

BMC medical informatics and decision making
BACKGROUND: Prompt-based learning involves the additions of prompts (i.e., templates) to the input of pre-trained large language models (PLMs) to adapt them to specific tasks with minimal training. This technique is particularly advantageous in clini...

Artificial intelligence policies in bioethics and health humanities: a comparative analysis of publishers and journals.

BMC medical ethics
INTRODUCTION: Rapid advancements in artificial intelligence (AI) pose novel ethical and practical challenges for scholarly publishing. Although AI-related policies are emerging in many disciplines, little is known about the extent and clarity of AI g...

Enhancing AI literacy in undergraduate pre-medical education through student associations: an educational intervention.

BMC medical education
BACKGROUND: The integration of artificial intelligence (AI) into healthcare is rapidly advancing, with profound implications for medical practice. However, a gap exists in formal AI education for pre-medical students. This study evaluates the effecti...

Development and external validation of machine learning models for the early prediction of malnutrition in critically ill patients: a prospective observational study.

BMC medical informatics and decision making
BACKGROUND: Early detection of malnutrition in critically ill patients is crucial for timely intervention and improved clinical outcomes. However, identifying individuals at risk remains challenging due to the complexity and variability of patient co...

Accurate prediction of synergistic drug combination using a multi-source information fusion framework.

BMC biology
BACKGROUND: Accurately predicting synergistic drug combinations is critical for complex disease therapy. However, the vast search space of potential drug combinations poses significant challenges for identification through biological experiments alon...

Interpretable machine learning analysis of immunoinflammatory biomarkers for predicting CHD among NAFLD patients.

Cardiovascular diabetology
BACKGROUND: Coronary Heart Disease (CHD) and Non-Alcoholic Fatty Liver Disease (NAFLD) share overlapping pathogenic mechanisms including adipose tissue dysfunction, insulin resistance, and systemic inflammation mediated by adipokines. However, the sp...

Construction and validation of a risk prediction model for chronic obstructive pulmonary disease (COPD): a cross-sectional study based on the NHANES database from 2009 to 2018.

BMC pulmonary medicine
BACKGROUND: Chronic obstructive pulmonary disease (COPD) is a major global public health concern, and early screening and identification of high-risk populations are critical for reducing the disease burden. Although several studies have explored the...

Network-based machine learning reveals cardiometabolic multimorbidity patterns and modifiable lifestyle factors: a community-focused analysis of NHANES 2015-2018.

BMC public health
Cardiometabolic Multimorbidity (CMM) has emerged as one of the primary threats to human health globally due to its high incidence, disability, and mortality rates. Accurate identification of CMM patterns is crucial for CMM classification and health m...