AIMC Topic: Humans

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Using Environmental Mixture Exposure-Triggered Biological Knowledge-Driven Machine Learning to Predict Early Pregnancy Loss.

Environmental science & technology
The assessment of how environmental mixture exposures affect reproductive health faces difficulties. While knowledge graph networks offer valuable advantages in biological interpretation and prediction, their application in epidemiological studies, p...

Mechanistic Insights into the Effects of Liquid Crystalline Monomers on Intestinal Stem Cell Differentiation Imbalance by Integrating Machine Learning and Adverse Outcome Pathway Framework Based on Organoids.

Environmental science & technology
The global annual output of liquid crystal monomers (LCMs) continues to increase, yet associated environmental and health risks remain poorly characterized. Assessing the toxic effects of the LCM mixture and individual components is critical for risk...

Sociohydrodynamics: Data-driven modeling of social behavior.

Proceedings of the National Academy of Sciences of the United States of America
Living systems display complex behaviors driven by physical forces as well as decision-making. Hydrodynamic theories hold promise for simplified universal descriptions of socially generated collective behaviors. However, the construction of such theo...

Disorganization of retinal inner layers as an optical coherence tomography biomarker in diabetic retinopathy: A review.

Indian journal of ophthalmology
Diabetic retinopathy is a leading cause of vision impairment globally. Disorganization of the retinal inner layers (DRIL), detected via optical coherence tomography, has emerged as a potential biomarker of disease severity and visual prognosis. This ...

Effects of attractions and social attributes on peoples' usage intention and media dependence towards chatbot: The mediating role of parasocial interaction and emotional support.

BMC psychology
PURPOSE: It is important to explore the relationship between humans and chatbots to improve human-robot interaction in the era of artificial intelligence. This study aims to explore the effects of attractions and social attributes of chatbots on user...

Predicting current habitat suitability for intermediate snail hosts of urogenital and intestinal schistosomiasis in the Lower Shire Valley floodplain of southern Malawi.

Parasites & vectors
BACKGROUND: Relating the geographical distribution of intermediate freshwater snail hosts (viz. vectors of schistosomes) to local environmental attributes offers value for understanding the epidemiological landscape of schistosomiasis transmission in...

Fusion model integrating multi-sequence MRI radiomics and habitat imaging for predicting pathological complete response in breast cancer treated with neoadjuvant therapy.

Cancer imaging : the official publication of the International Cancer Imaging Society
BACKGROUND: This study aimed to develop a predictive model integrating multi-sequence MRI radiomics, deep learning features, and habitat imaging to forecast pathological complete response (pCR) in breast cancer patients undergoing neoadjuvant therapy...

Significant correlation between ferroptosis-associated genes and ulcerative colitis: implications for diagnosis and treatment.

European journal of medical research
BACKGROUND: Ulcerative colitis (UC) is a significant type of inflammatory bowel disease (IBD). Ferroptosis is a type of procedural death that is associated with different types of diseases to various degrees. This study aimed to explore the key ferro...

Integrative single-cell and bulk transcriptomic analysis reveals the landscape of T cell mitotic catastrophe associated genes in esophageal squamous cell carcinoma.

Human genomics
BACKGROUND: Mitotic catastrophe (MC) is a well-recognized endogenous mechanism of tumor cell death, characterized as a delayed cell death process associated with aberrant mitosis. However, its prognostic significance in the context of intratumoral he...

Clinical-transcriptomic classification of lumbar disc degeneration enhanced by machine learning.

Military Medical Research
BACKGROUND: Lumbar disc degeneration (LDD) displays considerable heterogeneity in terms of clinical features and pathological changes. However, researchers have not clearly determined whether the transcriptome variations in LDD could be used to ident...