AIMC Topic: Humans

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Machine learning using clinical data at baseline predicts the efficacy of vedolizumab at week 22 in patients with ulcerative colitis.

Scientific reports
Predicting the response of patients with ulcerative colitis (UC) to a biologic such as vedolizumab (VDZ) before administration is an unmet need for optimizing individual patient treatment. We hypothesized that the machine-learning approach with daily...

Human activity recognition using wearable sensors, discriminant analysis, and long short-term memory-based neural structured learning.

Scientific reports
Healthcare using body sensor data has been getting huge research attentions by a wide range of researchers because of its good practical applications such as smart health care systems. For instance, smart wearable sensor-based behavior recognition sy...

Optimization of C-to-G base editors with sequence context preference predictable by machine learning methods.

Nature communications
Efficient and precise base editors (BEs) for C-to-G transversion are highly desirable. However, the sequence context affecting editing outcome largely remains unclear. Here we report engineered C-to-G BEs of high efficiency and fidelity, with the seq...

Deep learning-based transformation of H&E stained tissues into special stains.

Nature communications
Pathology is practiced by visual inspection of histochemically stained tissue slides. While the hematoxylin and eosin (H&E) stain is most commonly used, special stains can provide additional contrast to different tissue components. Here, we demonstra...

Potential of high dimensional radiomic features to assess blood components in intraaortic vessels in non-contrast CT scans.

BMC medical imaging
BACKGROUND: To assess the potential of radiomic features to quantify components of blood in intraaortic vessels to non-invasively predict moderate-to-severe anemia in non-contrast enhanced CT scans.

DeepG4: A deep learning approach to predict cell-type specific active G-quadruplex regions.

PLoS computational biology
DNA is a complex molecule carrying the instructions an organism needs to develop, live and reproduce. In 1953, Watson and Crick discovered that DNA is composed of two chains forming a double-helix. Later on, other structures of DNA were discovered an...

Comparative mapping of crawling-cell morphodynamics in deep learning-based feature space.

PLoS computational biology
Navigation of fast migrating cells such as amoeba Dictyostelium and immune cells are tightly associated with their morphologies that range from steady polarized forms that support high directionality to those more complex and variable when making fre...

Artificial Intelligence for Diagnosis and Gleason Grading of Prostate Cancer in Biopsies-Current Status and Next Steps.

European urology focus
Diagnosis and Gleason grading of prostate cancer in biopsies are critical for the clinical management of men with prostate cancer. Despite this, the high grading variability among pathologists leads to the potential for under- and overtreatment. Arti...

Memristor-Based Neural Network Circuit of Emotion Congruent Memory With Mental Fatigue and Emotion Inhibition.

IEEE transactions on biomedical circuits and systems
Most memristor-based neural networks only consider a single mode of memory or emotion, but ignore the relationship between emotion and memory. In this paper, a memristor-based neural network circuit of emotion congruent memory is proposed and verifie...

Cardiac Magnetic Resonance Images Superresolution via Multichannel Residual Attention Networks.

Computational and mathematical methods in medicine
The deep neural network has achieved good results in medical image superresolution. However, due to the medical equipment limitations and the complexity of the human body structure, it is difficult to reconstruct clear cardiac magnetic resonance (CMR...