AIMC Topic: Humans

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Two-step deep neural network for segmentation of deep white matter hyperintensities in migraineurs.

Computer methods and programs in biomedicine
BACKGROUND AND OBJECTIVE: Patients with migraine show an increased presence of white matter hyperintensities (WMHs), especially deep WMHs. Segmentation of small, deep WMHs is a critical issue in managing migraine care. Here, we aim to develop a novel...

Automated detection and classification of thyroid nodules in ultrasound images using clinical-knowledge-guided convolutional neural networks.

Medical image analysis
Accurate diagnosis of thyroid nodules using ultrasonography is a valuable but tough task even for experienced radiologists, considering both benign and malignant nodules have heterogeneous appearances. Computer-aided diagnosis (CAD) methods could pot...

CT Texture Analysis and Machine Learning Improve Post-ablation Prognostication in Patients with Adrenal Metastases: A Proof of Concept.

Cardiovascular and interventional radiology
INTRODUCTION: To assess the performance of pre-ablation computed tomography texture features of adrenal metastases to predict post-treatment local progression and survival in patients who underwent ablation using machine learning as a prediction tool...

A probabilistic method to estimate gait kinetics in the absence of ground reaction force measurements.

Journal of biomechanics
Human joint torques during gait are usually computed using inverse dynamics. This method requires a skeletal model, kinematics and measured ground reaction forces and moments (GRFM). Measuring GRFM is however only possible in a controlled environment...

Automatic segmentation of the uterus on MRI using a convolutional neural network.

Computers in biology and medicine
BACKGROUND: This study was performed to evaluate the clinical feasibility of a U-net for fully automatic uterine segmentation on MRI by using images of major uterine disorders.

Machine learning algorithms can classify outdoor terrain types during running using accelerometry data.

Gait & posture
BACKGROUND: Running is a popular physical activity that benefits health; however, running surface characteristics may influence loading impact and injury risk. Machine learning algorithms could automatically identify running surface from wearable mot...

Deep Learning-Based Histopathologic Assessment of Kidney Tissue.

Journal of the American Society of Nephrology : JASN
BACKGROUND: The development of deep neural networks is facilitating more advanced digital analysis of histopathologic images. We trained a convolutional neural network for multiclass segmentation of digitized kidney tissue sections stained with perio...

Improvement of Epitope Prediction Using Peptide Sequence Descriptors and Machine Learning.

International journal of molecular sciences
In this work, we improved a previous model used for the prediction of proteomes as new B-cell epitopes in vaccine design. The predicted epitope activity of a queried peptide is based on its sequence, a known reference epitope sequence under specific ...

Challenges in the construction of knowledge bases for human microbiome-disease associations.

Microbiome
The last few years have seen tremendous growth in human microbiome research, with a particular focus on the links to both mental and physical health and disease. Medical and experimental settings provide initial sources of information about these lin...