AIMC Topic: Humans

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The Missing Pieces of Artificial Intelligence in Medicine.

Trends in pharmacological sciences
Stakeholders across the entire healthcare chain are looking to incorporate artificial intelligence (AI) into their decision-making process. From early-stage drug discovery to clinical decision support systems, we have seen examples of how AI can impr...

Cancer classification and pathway discovery using non-negative matrix factorization.

Journal of biomedical informatics
OBJECTIVES: Extracting genetic information from a full range of sequencing data is important for understanding disease. We propose a novel method to effectively explore the landscape of genetic mutations and aggregate them to predict cancer type.

Exploring the druggable space around the Fanconi anemia pathway using machine learning and mechanistic models.

BMC bioinformatics
BACKGROUND: In spite of the abundance of genomic data, predictive models that describe phenotypes as a function of gene expression or mutations are difficult to obtain because they are affected by the curse of dimensionality, given the disbalance bet...

Attention-enabled 3D boosted convolutional neural networks for semantic CT segmentation using deep supervision.

Physics in medicine and biology
A deeply supervised attention-enabled boosted convolutional neural network (DAB-CNN) is presented as a superior alternative to current state-of-the-art convolutional neural networks (CNNs) for semantic CT segmentation. Spatial attention gates (AGs) w...

Application of machine learning to structural connectome to predict symptom reduction in depressed adolescents with cognitive behavioral therapy (CBT).

NeuroImage. Clinical
PURPOSE: Adolescent major depressive disorder (MDD) is a highly prevalent, incapacitating and costly illness. Many depressed teens do not improve with cognitive behavioral therapy (CBT), a first-line treatment for adolescent MDD, and face devastating...

A Real-Time Arrhythmia Heartbeats Classification Algorithm Using Parallel Delta Modulations and Rotated Linear-Kernel Support Vector Machines.

IEEE transactions on bio-medical engineering
Real-time wearable electrocardiogram monitoring sensor is one of the best candidates in assisting cardiovascular disease diagnosis. In this paper, we present a novel real-time machine learning system for Arrhythmia classification. The system is based...

Toward Safe Retinal Microsurgery: Development and Evaluation of an RNN-Based Active Interventional Control Framework.

IEEE transactions on bio-medical engineering
OBJECTIVE: Robotics-assisted retinal microsurgery provides several benefits including improvement of manipulation precision. The assistance provided to the surgeons by current robotic frameworks is, however, a "passive" support, e.g., by damping hand...

Novel adversarial semantic structure deep learning for MRI-guided attenuation correction in brain PET/MRI.

European journal of nuclear medicine and molecular imaging
OBJECTIVE: Quantitative PET/MR imaging is challenged by the accuracy of synthetic CT (sCT) generation from MR images. Deep learning-based algorithms have recently gained momentum for a number of medical image analysis applications. In this work, a no...

Neural Mechanisms for Accepting and Rejecting Artificial Social Partners in the Uncanny Valley.

The Journal of neuroscience : the official journal of the Society for Neuroscience
Artificial agents are becoming prevalent across human life domains. However, the neural mechanisms underlying human responses to these new, artificial social partners remain unclear. The uncanny valley (UV) hypothesis predicts that humans prefer anth...