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Inferring MicroRNA Targets Based on Restricted Boltzmann Machines.

IEEE journal of biomedical and health informatics
Predicting the miRNA-target interactions (MTIs) is a critical task for elucidating mechanistic roles of miRNAs in pathophysiology. However, most existing techniques have a higher false positive because the precise miRNA target mechanisms are poorly k...

Detecting Vascular Age Using the Analysis of Peripheral Pulse.

IEEE transactions on bio-medical engineering
UNLABELLED: Vascular ageing is known to be accompanied by arterial stiffening and vascular endothelial dysfunction, and represents an independent factor contributing to the development of cardiovascular disease. The microvascular pulse is affected by...

Medical Image Synthesis with Deep Convolutional Adversarial Networks.

IEEE transactions on bio-medical engineering
Medical imaging plays a critical role in various clinical applications. However, due to multiple considerations such as cost and radiation dose, the acquisition of certain image modalities may be limited. Thus, medical image synthesis can be of great...

Learning Temporal Information for Brain-Computer Interface Using Convolutional Neural Networks.

IEEE transactions on neural networks and learning systems
Deep learning (DL) methods and architectures have been the state-of-the-art classification algorithms for computer vision and natural language processing problems. However, the successful application of these methods in motor imagery (MI) brain-compu...

A convolutional neural network to filter artifacts in spectroscopic MRI.

Magnetic resonance in medicine
PURPOSE: Proton MRSI is a noninvasive modality capable of generating volumetric maps of in vivo tissue metabolism without the need for ionizing radiation or injected contrast agent. Magnetic resonance spectroscopic imaging has been shown to be a viab...

Multichannel lung sound analysis for asthma detection.

Computer methods and programs in biomedicine
BACKGROUND AND OBJECTIVE: Lung sound signals convey valuable information of the lung status. Auscultation is an effective technique to appreciate the condition of the respiratory system using lung sound signals. The prior works on asthma detection fr...

Age-related changes in the ease of dynamical transitions in human brain activity.

Human brain mapping
Executive functions, a set of cognitive processes that enable flexible behavioral control, are known to decay with aging. Because such complex mental functions are considered to rely on the dynamic coordination of functionally different neural system...

Knee menisci segmentation using convolutional neural networks: data from the Osteoarthritis Initiative.

Osteoarthritis and cartilage
OBJECTIVE: To present a novel method for automated segmentation of knee menisci from MRIs. To evaluate quantitative meniscal biomarkers for osteoarthritis (OA) estimated thereof.

Structure-function properties of hypolipidemic peptides.

Journal of food biochemistry
This review addresses the structure-function properties of hypolipidemic peptides. The cholesterol-lowering peptide (lactostatin: IIAEK) operates via a new regulatory pathway in the calcium-channel-related mitogen-activated protein kinase (MAPK) sign...

Development on a magnetic anchoring robot system based on visual servo control for laparoendoscopic single-site surgery.

The international journal of medical robotics + computer assisted surgery : MRCAS
BACKGROUND: Surgical robot systems have been used in laparoendoscopic single-site surgery (LESS) to improve patient outcomes. A magnetic anchoring surgical robot system for LESS can effectively extend the operation space.
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