AIMC Topic: Hypoxia

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Machine learning analysis of DNA methylation in a hypoxia-immune model of oral squamous cell carcinoma.

International immunopharmacology
BACKGROUND: Hypoxia status and immunity are related with the development and prognosis of oral squamous cell carcinoma (OSCC). Here, we constructed a hypoxia-immune model to explore its upstream mechanism and identify potential CpG sites.

Resting-State Brain Activity for Early Prediction Outcome in Postanoxic Patients in a Coma with Indeterminate Clinical Prognosis.

AJNR. American journal of neuroradiology
BACKGROUND AND PURPOSE: Early outcome prediction of postanoxic patients in a coma after cardiac arrest proves challenging. Current prognostication relies on multimodal testing, using clinical examination, electrophysiologic testing, biomarkers, and s...

An artificial neural network model for prediction of hypoxemia during sedation for gastrointestinal endoscopy.

The Journal of international medical research
OBJECTIVE: This study was designed to assess clinical predictors of hypoxemia and develop an artificial neural network (ANN) model for prediction of hypoxemia during sedation for gastrointestinal endoscopy examination.

Explainable machine-learning predictions for the prevention of hypoxaemia during surgery.

Nature biomedical engineering
Although anaesthesiologists strive to avoid hypoxemia during surgery, reliably predicting future intraoperative hypoxemia is not currently possible. Here, we report the development and testing of a machine-learning-based system that, in real time dur...

Artificial neural network classifier predicts neuroblastoma patients' outcome.

BMC bioinformatics
BACKGROUND: More than fifty percent of neuroblastoma (NB) patients with adverse prognosis do not benefit from treatment making the identification of new potential targets mandatory. Hypoxia is a condition of low oxygen tension, occurring in poorly va...

Development and experimental verification of a prognosis model for hypoxia- and lactate metabolism-associated genes in HNSCC.

Medicine
Hypoxia and lactate metabolism are both distinctive characteristics of cancerous cells. Head and neck squamous cell carcinoma (HNSCC) is one of the most prevalent forms of cancer. The objective of this study was to construct a prognostic model of gen...

A Comparative Analysis of Federated and Centralized Learning for SpO2 Prediction in Five Critical Care Databases.

Studies in health technology and informatics
This study explores the potential of federated learning (FL) to develop a predictive model of hypoxemia in intensive care unit (ICU) patients. Centralized learning (CL) and local learning (LL) approaches have been limited by the localized nature of d...

Machine Learning Model Combining Ventilatory, Hypoxic, Arousal Domains Across Sleep Better Predicts Adverse Consequences of Obstructive Sleep Apnea.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Obstructive sleep apnea(OSA) severity is currently assessed clinically using the apnea-hypopnea index (AHI), which is inconsistently associated with short- and long-term outcomes. Ventilatory, hypoxic, and arousal domains are known to exhibit abnorma...

A deep learning approach for automation in neurite tracing and cell size estimation from differential contrast images under healthy and hypoxic condition.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Chronic hypoxia is known to be a major cause of neurite length retraction followed be degeneration. Specifically, laser scanning confocal microscopy (LSCM) based-contrast imaging is used for monitoring neuronal morphology under hypoxic condition. Alt...