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Leptin

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Leptin levels in childhood tuberculosis and its correlation with body mass index, IFN-γ, and TNF-α in an Indonesian population.

The Indian journal of tuberculosis
BACKGROUND: Leptin plays a key role in the regulation of energy and inflammation in tuberculosis (TB). However, its correlation in children with TB remains unclear. Therefore, this study aimed to evaluate the correlations between body mass index, IFN...

[Leptin sexual dimorphism, insulin resistance, and body composition in normal weight prepubescent].

Revista chilena de pediatria
INTRODUCTION: The prepubertal stage is a critical period of body fat development, in which leptin and insulin re sistance has been associated, however, there are few studies in normal-weight prepubescents. Ob jective: To assess the relationship betwe...

Serum adipocytokines are associated with microalbuminuria in patients with type 1 diabetes and incipient chronic complications.

Diabetes & metabolic syndrome
AIMS: Recent studies have implicated possible contribution of adipocytokines in development and progression of microvascular complications in patients with type 1 diabetes (T1DM). The aim of our study was to investigate relationship between adipocyto...

Leptin Stimulates Prolactin mRNA Expression in the Goldfish Pituitary through a Combination of the PI3K/Akt/mTOR, MKK/pMAPK and MEK/ERK Signalling Pathways.

International journal of molecular sciences
Leptin actions at the pituitary level have been extensively investigated in mammalian species, but remain insufficiently characterized in lower vertebrates, especially in teleost fish. Prolactin (PRL) is a pituitary hormone of central importance to o...

Expression of AdipoR1 and AdipoR2 Receptors as Leptin-Breast Cancer Regulation Mechanisms.

Disease markers
The development of breast cancer is influenced by the adipose tissue through the proteins leptin and adiponectin. However, there is little research concerning AdipoR1 and AdipoR2 receptors and the influence of leptin over them. The objective of this ...

Caloric restriction and IGF-I administration promote rabbit fecundity: Possible interrelationships and mechanisms of action.

Theriogenology
The aim of these in vivo and in vitro studies was to examine the influence of caloric restriction (CR), and the administration of insulin-like growth factor (IGF-I), on rabbit fecundity and to understand the interrelationships between CR and IGF-I, a...

The association between clinically suspect arthralgia and adipokines in obese patients.

Acta reumatologica portuguesa
OBJECTIVE: Obesity is a moderate low-grade chronic inflammatory condition. The cause of low-grade inflammation in obese patients who have clinically suspect arthralgia (CSA) may be the subject of debate in clinical practice. Our aim is to determine w...

Evidence for Alteration in Serum Concentrations of Leptin in Infertile Men Categorized Based on BMI.

Clinical laboratory
BACKGROUND: The aim of this study is to compare serum and seminal level of leptin in the context of infertility in men according to BMI. We also investigated the possible correlation of circulating level of leptin with fertility indices.

Estimation of umbilical cord blood leptin and insulin based on anthropometric data by means of artificial neural network approach: identifying key maternal and neonatal factors.

BMC pregnancy and childbirth
BACKGROUND: Leptin and insulin levels are key factors regulating fetal and neonatal energy homeostasis, development and growth. Both biomarkers are used as predictors of weight gain and obesity during infancy. There are currently no prediction algori...