Major advances in managing critically ill patients with liver disease have improved their prognosis and access to intensive care facilities. Acute-on-chronic liver failure (ACLF) is now a well-defined disease and these patients can be fast-tracked fo...
A major histologic feature of cirrhosis is the loss of liver architecture with collapse of tissue and vascular changes per unit. We developed qVessel to quantify the arterial density (AD) in liver biopsies with chronic disease of varied etiology and ...
Advancements in omics technologies and artificial intelligence (AI) methodologies are fuelling our progress towards personalised diagnosis, prognosis and treatment strategies in hepatology. This review provides a comprehensive overview of the current...
Medical & biological engineering & computing
Jan 13, 2025
In the context of chronic liver diseases, where variability in progression necessitates early and precise diagnosis, this study addresses the limitations of traditional histological analysis and the shortcomings of existing deep learning approaches. ...
BACKGROUND: Chronic liver disease (CLD) is a substantial cause of morbidity and mortality worldwide. Liver stiffness, as measured by MR elastography (MRE), is well-accepted as a surrogate marker of liver fibrosis.
Interdisciplinary sciences, computational life sciences
Nov 19, 2024
Yinchenhao Decoction (YCHD), a classic formula in traditional Chinese medicine, is believed to have the potential to treat liver diseases by modulating the Toll-like receptor 4 (TLR4) target. Therefore, a thorough exploration of the effective compone...
Journal of gastroenterology and hepatology
Nov 14, 2024
BACKGROUND AND AIM: Computed tomography of the abdomen exhibits subtle and complex features of liver lesions, subjectively interpreted by physicians. We developed a deep learning-based localization and classification (DLLC) system for focal liver les...
PURPOSE: The purpose of this study was to investigate whether the high-precision magnetic resonance (MR) sequence using modified Fast 3D mode wheel and Precise IQ Engine (PIQE), that was collected in a wheel shape with sequential data filling in the ...
IEEE journal of translational engineering in health and medicine
Nov 4, 2024
To achieve precise Couinaud liver segmentation in preoperative planning for hepatic surgery, accommodating the complex anatomy and significant variations, optimizing surgical approaches, reducing postoperative complications, and preserving liver func...
The Kaohsiung journal of medical sciences
Oct 23, 2024
Universal neonatal hepatitis B virus (HBV) vaccination and the advent of direct-acting antivirals (DAA) against hepatitis C virus (HCV) have reshaped the epidemiology of chronic liver diseases. However, some aspects of the management of chronic liver...
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