AIMC Topic: Liver Diseases

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Discovery of Active Ingredient of Yinchenhao Decoction Targeting TLR4 for Hepatic Inflammatory Diseases Based on Deep Learning Approach.

Interdisciplinary sciences, computational life sciences
Yinchenhao Decoction (YCHD), a classic formula in traditional Chinese medicine, is believed to have the potential to treat liver diseases by modulating the Toll-like receptor 4 (TLR4) target. Therefore, a thorough exploration of the effective compone...

Automatic localization and deep convolutional generative adversarial network-based classification of focal liver lesions in computed tomography images: A preliminary study.

Journal of gastroenterology and hepatology
BACKGROUND AND AIM: Computed tomography of the abdomen exhibits subtle and complex features of liver lesions, subjectively interpreted by physicians. We developed a deep learning-based localization and classification (DLLC) system for focal liver les...

High-precision MRI of liver and hepatic lesions on gadoxetic acid-enhanced hepatobiliary phase using a deep learning technique.

Japanese journal of radiology
PURPOSE: The purpose of this study was to investigate whether the high-precision magnetic resonance (MR) sequence using modified Fast 3D mode wheel and Precise IQ Engine (PIQE), that was collected in a wheel shape with sequential data filling in the ...

A Multi-Task Based Deep Learning Framework With Landmark Detection for MRI Couinaud Segmentation.

IEEE journal of translational engineering in health and medicine
To achieve precise Couinaud liver segmentation in preoperative planning for hepatic surgery, accommodating the complex anatomy and significant variations, optimizing surgical approaches, reducing postoperative complications, and preserving liver func...

The role of artificial intelligence in the management of liver diseases.

The Kaohsiung journal of medical sciences
Universal neonatal hepatitis B virus (HBV) vaccination and the advent of direct-acting antivirals (DAA) against hepatitis C virus (HCV) have reshaped the epidemiology of chronic liver diseases. However, some aspects of the management of chronic liver...

Artificial intelligence for detection and characterization of focal hepatic lesions: a review.

Abdominal radiology (New York)
Focal liver lesions (FLL) are common incidental findings in abdominal imaging. While the majority of FLLs are benign and asymptomatic, some can be malignant or pre-malignant, and need accurate detection and classification. Current imaging techniques,...

Polynomial-SHAP analysis of liver disease markers for capturing of complex feature interactions in machine learning models.

Computers in biology and medicine
Liver disease diagnosis is pivotal for effective patient management, and machine learning techniques have shown promise in this domain. In this study, we investigate the impact of Polynomial-SHapley Additive exPlanations analysis on enhancing the per...

Training robust T1-weighted magnetic resonance imaging liver segmentation models using ensembles of datasets with different contrast protocols and liver disease etiologies.

Scientific reports
Image segmentation of the liver is an important step in treatment planning for liver cancer. However, manual segmentation at a large scale is not practical, leading to increasing reliance on deep learning models to automatically segment the liver. Th...

Deep Learning Based Shear Wave Detection and Segmentation Tool for Use in Point-of-Care for Chronic Liver Disease Assessments.

Ultrasound in medicine & biology
OBJECTIVE: As metabolic dysfunction-associated steatotic liver disease (MASLD) becomes more prevalent worldwide, it is imperative to create more accurate technologies that make it easy to assess the liver in a point-of-care setting. The aim of this s...

AI-based automation of enrollment criteria and endpoint assessment in clinical trials in liver diseases.

Nature medicine
Clinical trials in metabolic dysfunction-associated steatohepatitis (MASH, formerly known as nonalcoholic steatohepatitis) require histologic scoring for assessment of inclusion criteria and endpoints. However, variability in interpretation has impac...