BACKGROUND: Proton therapy is commonly used for treating hepatocellular carcinoma (HCC); however, its feasibility can be challenging to assess in large tumors or those adjacent to critical organs at risk (OARs), which are typically assessed only afte...
Primary liver cancer is the sixth most commonly diagnosed cancer globally and the third leading cause of cancer-related deaths. Hepatocellular carcinoma (HCC) is the most common type of primary liver cancer, and microvascular invasion (MVI) is a sign...
O-glycosylation significantly influences cellular physiological processes and disease regulation by modulating the structure, function, and stability of proteins. However, there is a notable gap in research focusing on O-glycosylation in relation to ...
Hyperspectral imaging (HSI) holds significant potential for transforming the field of computational pathology. However, the number of HSI-based research studies remains limited, and in many cases, the advantages of HSI over traditional RGB imaging ha...
Hepatitis B virus (HBV) infection is a major driver of hepatocellular carcinoma (HCC), yet the mechanisms by which HBV triggers HCC and how it interacts with the immune system remain largely undefined. In this study, 53 immune-related key genes invol...
Journal of cancer research and clinical oncology
Jul 17, 2025
Precise liver segmentation is critical for accurate diagnosis and effective treatment planning, serving as a foundation for medical image analysis. However, existing methods struggle with limited labeled data, poor generalizability, and insufficient ...
Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society
Jul 16, 2025
Hepatocellular carcinoma (HCC) is a major global health concern, with microvascular invasion (MVI) being a critical prognostic factor linked to early recurrence and poor survival. Preoperative MVI prediction remains challenging, but recent advancemen...
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver
Jul 15, 2025
BACKGROUND: Survival of patients with high-risk hepatoblastoma remains low, and early identification of high-risk hepatoblastoma is critical.
BACKGROUND: Hepatocellular carcinoma (HCC) is the fifth most common cancer worldwide and the third most common cause of cancer-related death. Cirrhosis is a major contributing factor, accounting for over 90% of HCC cases. With the high mortality rate...
Hepatocellular carcinoma (HCC) progression and prognosis are influenced by various molecular markers. This study aimed to identify the hub gene associated with HCC clinical characteristics and its role in HCC progression. Differentially expressed gen...
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