AIMC Topic: Lung Neoplasms

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Non-invasive Prediction of Lymph Node Metastasis in NSCLC Using Clinical, Radiomics, and Deep Learning Features From F-FDG PET/CT Based on Interpretable Machine Learning.

Academic radiology
PURPOSE: This study aimed to develop and evaluate a machine learning model combining clinical, radiomics, and deep learning features derived from PET/CT imaging to predict lymph node metastasis (LNM) in patients with non-small cell lung cancer (NSCLC...

Spectrum of errors in nodule detection and characterization using machine learning: A pictorial essay.

Current problems in diagnostic radiology
In academic and research settings, computer-aided nodule detection software has been shown to increase accuracy, efficiency, and throughput. However, radiologists need to be familiar with the spectrum of errors that can occur when these algorithms ar...

Utility of a Large Language Model for Extraction of Clinical Findings from Healthcare Data following Lung Ablation: A Feasibility Study.

Journal of vascular and interventional radiology : JVIR
To assess the feasibility of utilizing a large language model (LLM) in extracting clinically relevant information from healthcare data in patients who have undergone microwave ablation for lung tumors. In this single-center retrospective study, radio...

Deep learning using histological images for gene mutation prediction in lung cancer: a multicentre retrospective study.

The Lancet. Oncology
BACKGROUND: Accurate detection of driver gene mutations is crucial for treatment planning and predicting prognosis for patients with lung cancer. Conventional genomic testing requires high-quality tissue samples and is time-consuming and resource-con...

Self-supervised learning improves robustness of deep learning lung tumor segmentation models to CT imaging differences.

Medical physics
BACKGROUND: Self-supervised learning (SSL) is an approach to extract useful feature representations from unlabeled data, and enable fine-tuning on downstream tasks with limited labeled examples. Self-pretraining is a SSL approach that uses curated do...

Machine learning-aided discovery of T790M-mutant EGFR inhibitor CDDO-Me effectively suppresses non-small cell lung cancer growth.

Cell communication and signaling : CCS
BACKGROUND: Epidermal growth factor receptor (EGFR) T790M mutation often occurs during long durational erlotinib treatment of non-small cell lung cancer (NSCLC) patients, leading to drug resistance and disease progression. Identification of new selec...

Predicting cancer content in tiles of lung squamous cell carcinoma tumours with validation against pathologist labels.

Computers in biology and medicine
BACKGROUND: A growing body of research is using deep learning to explore the relationship between treatment biomarkers for lung cancer patients and cancer tissue morphology on digitized whole slide images (WSIs) of tumour resections. However, these W...

Advancing cancer diagnosis and prognostication through deep learning mastery in breast, colon, and lung histopathology with ResoMergeNet.

Computers in biology and medicine
Cancer, a global health threat, demands effective diagnostic solutions to combat its impact on public health, particularly for breast, colon, and lung cancers. Early and accurate diagnosis is essential for successful treatment, prompting the rise of ...

Automated derivation of diagnostic criteria for lung cancer using natural language processing on electronic health records: a pilot study.

BMC medical informatics and decision making
BACKGROUND: The digitisation of healthcare records has generated vast amounts of unstructured data, presenting opportunities for improvements in disease diagnosis when clinical coding falls short, such as in the recording of patient symptoms. This st...

Research Trends of Artificial Intelligence in Lung Cancer: A Combined Approach of Analysis With Latent Dirichlet Allocation and HJ-Biplot Statistical Methods.

Pulmonary medicine
Lung cancer (LC) remains one of the leading causes of cancer-related mortality worldwide. With recent technological advances, artificial intelligence (AI) has begun to play a crucial role in improving diagnostic and treatment methods. It is crucial t...