AIMC Topic: Machine Learning

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Comparison of machine learning algorithms for predicting length of stay in chronic kidney disease patients.

Computers in biology and medicine
The length of stay (LOS) for patients in hospitals is crucial for workforce planning, resource allocation, and bed capacity management, impacting healthcare costs, future needs and financial planning. This study focuses on calculating the LOS for Chr...

Augmenting Chemical Databases for Atomistic Machine Learning by Sampling Conformational Space.

Journal of chemical information and modeling
Machine learning (ML) has become a standard tool for the exploration of the chemical space. Much of the performance of such models depends on the chosen database for a given task. Here, this aspect is investigated for "chemical tasks" including the p...

A Molecular Representation Learning Model Based on Multidimensional Joint and Cross-Learning for Drug-Drug Interaction Prediction.

Journal of chemical information and modeling
Drug-drug interactions (DDIs) present significant challenges within clinical pharmacology, as they can impact therapeutic outcomes, especially given the growing prevalence of polypharmacy. Traditional methods for the clinical validation of DDIs typic...

Prediction of the hypothalamus-pituitary organoid formation using machine learning.

Cell reports methods
Multi-cellular organoids are self-assembly aggregates that mimic biological functions and developmental processes of many tissue types in vitro. They are widely employed for disease modeling and functional studies. Hypothalamus-pituitary organoids ca...

Integrated multiple machine learning and Mendelian randomization reveal LTF gene as a prognostic biomarker for nonspecific orbital inflammation.

BMC pharmacology & toxicology
BACKGROUND: Nonspecific orbital inflammation (NSOI), also known as idiopathic orbital inflammation, comprises a heterogeneous group of immune-mediated disorders affecting orbital tissues, unified by the absence of a defined etiology. Lactotransferrin...

An open dataset and machine learning algorithms for Niacin Skin-Flushing Response based screening of psychiatric disorders.

BMC psychiatry
BACKGROUND: Niacin Skin-Flushing Response (NSR) has emerged as a promising objective biomarker for the precise diagnosis of mental disorders. However, its diagnostic potential has been constrained by the limitations of traditional statistical approac...

Machine learning of whole-brain resting-state fMRI signatures for individualized grading of frontal gliomas.

Cancer imaging : the official publication of the International Cancer Imaging Society
PURPOSE: Accurate preoperative grading of gliomas is critical for therapeutic planning and prognostic evaluation. We developed a noninvasive machine learning model leveraging whole-brain resting-state functional magnetic resonance imaging (rs-fMRI) b...

Machine learning algorithms for risk factor selection with application to 60-day sepsis morbidity risk for a geriatric hip fracture cohort.

BMC geriatrics
BACKGROUND: Sepsis after hip fracture in elderly people is a risk factor for mortality. The purpose of this study was to screen for risk factors for 60-day sepsis morbidity after hip fracture and to establish a predictive model using various machine ...

Open-radiomics: a collection of standardized datasets and a technical protocol for reproducible radiomics machine learning pipelines.

BMC medical imaging
BACKGROUND: As an important branch of machine learning pipelines in medical imaging, radiomics faces two major challenges namely reproducibility and accessibility. In this work, we introduce open-radiomics, a set of radiomics datasets along with a co...

Diagnostic systematic review and meta-analysis of machine learning in predicting biochemical recurrence of prostate cancer.

Scientific reports
Prostate cancer (PCa) is the most prevalent malignant tumor in males, and many patients remain at risk of biochemical recurrence (BCR) following initial treatment. Accurate prediction of BCR is vital for effective clinical management and treatment pl...