AIMC Topic: Machine Learning

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Development and external validation of a machine learning model to predict bronchopulmonary dysplasia using dynamic factors.

Scientific reports
We hypothesized that incorporating postnatal dynamic factors would enhance the prediction accuracy of bronchopulmonary dysplasia in preterm infants. This retrospective cohort study included neonates born before 32 weeks of gestation at Seoul National...

Identification of gene signatures associated with lactation for predicting prognosis and treatment response in breast cancer patients through machine learning.

Scientific reports
As a newly discovered histone modification, abnormal lactation has been found to be present in and contribute to the development of various cancers. The aim of this study was to investigate the potential role between lactylation and the prognosis of ...

Utilizing artificial intelligence to predict and analyze socioeconomic, environmental, and healthcare factors driving tuberculosis globally.

Scientific reports
Tuberculosis (TB) is a major global health issue, contributing significantly to mortality and morbidity rates worldwide. Socioeconomic, environmental, and healthcare factors significantly impact TB trends. Therefore, we aimed to predict TB and identi...

Integrative analysis of signaling and metabolic pathways, immune infiltration patterns, and machine learning-based diagnostic model construction in major depressive disorder.

Scientific reports
Major depressive disorder (MDD) is a multifactorial disorder involving genetic and environmental factors, with unclear pathogenesis. This study aims to explore the pathogenic pathway of MDD and its relationship with immune responses and to discover i...

Explainable machine learning for predicting lung metastasis of colorectal cancer.

Scientific reports
Patients with lung metastasis of colorectal cancer typically have a poor prognosis. Therefore, establishing an effective screening and diagnosis model is paramount. Our study seeks to construct and verify a predictive model utilizing machine learning...

Identification and validation of a novel machine learning model for predicting severe pelvic endometriosis: A retrospective study.

Scientific reports
This study aimed to explore potential risk factors for severe endometriosis and to develop a model to predict the risk of severe endometriosis. A total of 308 patients with endometriosis were analyzed. Least absolute shrinkage and selection operator ...

Machine learning-based multiparametric CT radiomics for predicting microvascular invasion before nephrectomy in clear cell renal cell carcinoma.

Abdominal radiology (New York)
PURPOSE: This study aimed to investigate the value of integrating computed tomography (CT)-based tumor radiomics features with clinical parameters for preoperative prediction of microvascular invasion (MVI) in clear cell renal cell carcinoma (ccRCC).

In-silico investigation integrated with machine learning to identify potential inhibitors targeting AKT2: Key driver of cancer cell progression and metastasis.

Computer methods and programs in biomedicine
BACKGROUND AND OBJECTIVE: In search of a key driver for the invasive growth of cancer metastasis, AKT2 is found to be exceptionally expressed in colorectal cancer and its metastasis. Again, exceeding genomic arrangements of AKT2 can be held responsib...

Machine Learning-Based Diagnostic Prediction Model Using T1-Weighted Striatal Magnetic Resonance Imaging for Early-Stage Parkinson's Disease Detection.

Academic radiology
RATIONALE AND OBJECTIVES: Diagnosing Parkinson's disease (PD) typically relies on clinical evaluations, often detecting it in advanced stages. Recently, artificial intelligence has increasingly been applied to imaging for neurodegenerative disorders....

A random forest-based predictive model for classifying BRCA1 missense variants: a novel approach for evaluating the missense mutations effect.

Journal of human genetics
The right classification of variants is the key to pre-symptomatic detection of disease and conducting preventive actions. Since BRCA1 has a high incidence and penetrance in breast and ovarian cancers, a high-performance predictive tool can be employ...