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An immune-related gene signature for determining Ewing sarcoma prognosis based on machine learning.

Journal of cancer research and clinical oncology
PURPOSE: Ewing sarcoma (ES) is one of the most common malignant bone tumors in children and adolescents. The immune microenvironment plays an important role in the development of ES. Here, we developed an optimal signature for determining ES patient ...

Intensity harmonization techniques influence radiomics features and radiomics-based predictions in sarcoma patients.

Scientific reports
Intensity harmonization techniques (IHT) are mandatory to homogenize multicentric MRIs before any quantitative analysis because signal intensities (SI) do not have standardized units. Radiomics combine quantification of tumors' radiological phenotype...

Lymph node metastasis prediction of papillary thyroid carcinoma based on transfer learning radiomics.

Nature communications
Non-invasive assessment of the risk of lymph node metastasis (LNM) in patients with papillary thyroid carcinoma (PTC) is of great value for the treatment option selection. The purpose of this paper is to develop a transfer learning radiomics (TLR) mo...

Performance of a Deep Learning Algorithm Compared with Radiologic Interpretation for Lung Cancer Detection on Chest Radiographs in a Health Screening Population.

Radiology
Background The performance of a deep learning algorithm for lung cancer detection on chest radiographs in a health screening population is unknown. Purpose To validate a commercially available deep learning algorithm for lung cancer detection on ches...

Deep learning-based triage and analysis of lesion burden for COVID-19: a retrospective study with external validation.

The Lancet. Digital health
BACKGROUND: Prompt identification of patients suspected to have COVID-19 is crucial for disease control. We aimed to develop a deep learning algorithm on the basis of chest CT for rapid triaging in fever clinics.

Tracking historical changes in trustworthiness using machine learning analyses of facial cues in paintings.

Nature communications
Social trust is linked to a host of positive societal outcomes, including improved economic performance, lower crime rates and more inclusive institutions. Yet, the origins of trust remain elusive, partly because social trust is difficult to document...

Identification of risk features for complication in Gaucher's disease patients: a machine learning analysis of the Spanish registry of Gaucher disease.

Orphanet journal of rare diseases
BACKGROUND: Since enzyme replacement therapy for Gaucher disease (MIM#230800) has become available, both awareness of and the natural history of the disease have changed. However, there remain unmet needs such as the identification of patients at ris...

Alcoholic liver disease: A registry view on comorbidities and disease prediction.

PLoS computational biology
Alcoholic-related liver disease (ALD) is the cause of more than half of all liver-related deaths. Sustained excess drinking causes fatty liver and alcohol-related steatohepatitis, which may progress to alcoholic liver fibrosis (ALF) and eventually to...

Classification of normal sinus rhythm, abnormal arrhythmia and congestive heart failure ECG signals using LSTM and hybrid CNN-SVM deep neural networks.

Computer methods in biomechanics and biomedical engineering
Effective monitoring of heart patients according to heart signals can save a huge amount of life. In the last decade, the classification and prediction of heart diseases according to ECG signals has gained great importance for patients and doctors. I...