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Comparative analysis of pre-transcatheter aortic valve implantation CTA protocols: Optimizing radiation dose and contrast volume.

International journal of cardiology
BACKGROUND: To establish the most effective and safe pre-transcatheter aortic valve implantation (TAVI) CT angiography (CTA) protocol by comparing two approaches in terms of image quality, radiation and contrast dose.

Study of the sensory profile of Coffea canephora through malting/fermentation using HS-SPME-GC-MS and synthetic sampling combined with random forest.

Food chemistry
The sensory attributes of Coffea canephora beverages depend on the chemical composition of the bean, especially to the content of volatile organic compounds (VOCs). However, the relative abundance of these compounds may vary with the stage of bean ma...

DPP-IV inhibitory peptides from highland barley via machine learning and multi-scale validation.

Food chemistry
Highland barley has shown potential in regulating blood glucose and may serve as a natural source of dipeptidyl peptidase-IV (DPP-IV) inhibitors. In this study, machine learning (Gradient Boosting Decision Trees) and virtual screening were employed t...

Machine learning-based hemodynamics quantitative assessment of pulmonary circulation using computed tomographic pulmonary angiography.

International journal of cardiology
BACKGROUND: Pulmonary hypertension (pH) is a malignant pulmonary circulation disease. Right heart catheterization (RHC) is the gold standard procedure for quantitative evaluation of pulmonary hemodynamics. Accurate and noninvasive quantitative evalua...

Inflammatory biomarkers as predictors for unlocking antidepressant efficacy: Assessing predictive value and risk stratification in major depressive disorder in a prospective longitudinal study.

Journal of affective disorders
BACKGROUND: Major depressive disorder (MDD) is characterized by significant heterogeneity in treatment response, with inflammation hypothesized to play a role in its pathophysiology. Peripheral inflammatory biomarkers, such as the neutrophil-to-lymph...

Development of AI-integrated smartphone sponge-based sensors utilizing His@Co-NC nanozymes for highly sensitive sarcosine detection.

Biosensors & bioelectronics
The increasing demand for point-of-care detection of low-concentration cancer biomarkers has necessitated the development of innovative nanozyme-based sensing technologies. Here, a smartphone-integrated platform is presented that utilizes artificial ...

The risk factors for relapse behavior in individuals with substance use disorders: An interpretable machine learning study.

Journal of affective disorders
BACKGROUND: Substance abuse has become a serious public health problem worldwide, and finding effective prevention and treatment strategies is undoubtedly an urgent need. This study addresses the risk factors that lead to relapse behaviors among subs...

Machine learning models of depression in middle-aged and older adults with cardiovascular metabolic diseases.

Journal of affective disorders
BACKGROUND: The incidence of cardiovascular metabolic diseases (CMD) is increasing, and depression in CMD patients significantly impacts prognosis. Therefore, this study aimed to develop and validate a predictive model for depression in CMD patients ...

Functional connectome-based predictive modeling of suicidal ideation.

Journal of affective disorders
Suicide represents an egregious threat to society despite major advancements in medicine, in part due to limited knowledge of the biological mechanisms of suicidal behavior. We apply a connectome predictive modeling machine learning approach to ident...