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Cerebrospinal fluid inflammatory cytokines as prognostic indicators for cognitive decline across Alzheimer's disease spectrum.

Journal of Alzheimer's disease : JAD
BackgroundNeuroinflammation actively contributes to the pathophysiology of Alzheimer's disease (AD); however, the value of neuroinflammatory biomarkers for disease-staging or predicting disease progression remains unclear.ObjectiveTo investigate diag...

Using deep learning for estimation of time-since-injury in pediatric accidental fractures.

Pediatric radiology
BACKGROUND: Estimating time-since-injury of healing fractures is imprecise, encompassing excessively wide timeframes. Most injured children are evaluated at non-children's hospitals, yet pediatric radiologists can disagree with up to one in six skele...

Machine learning to risk stratify chest pain patients with non-diagnostic electrocardiogram in an Asian emergency department.

Annals of the Academy of Medicine, Singapore
INTRODUCTION: Elevated troponin, while essential for diagnosing myocardial infarction, can also be present in non-myocardial infarction conditions. The myocardial-ischaemic-injury-index (MI3) algorithm is a machine learning algorithm that considers a...

Fast and effective assessment for individuals with special needs form optimization and prediction models.

BMC psychology
The aim of this study was to determine which items in the psychological assessment forms used by counselling and research centres for individuals with special needs are effective in classifying individuals into special needs diagnostic categories. Da...

A wearable ankle-assisted robot for improving gait function and pattern in stroke patients.

Journal of neuroengineering and rehabilitation
BACKGROUND: Hemiplegic gait after a stroke can result in a decreased gait speed and asymmetrical gait pattern. Normal gait patterns and speed are typically the ultimate goals of gait function in stroke rehabilitation. The purpose of this study was to...

Explainable machine learning algorithm to predict cardiovascular event in patients undergoing peritoneal dialysis.

BMC medical informatics and decision making
OBJECTIVE: To compare the performance of predictive models for cardiovascular event (CVE) in patients undergoing peritoneal dialysis (PD) based on machine learning algorithm and Cox proportional hazard regression.

Deep learning for automated segmentation of brain edema in meningioma after radiosurgery.

BMC medical imaging
BACKGROUND: Although gamma Knife radiosurgery (GKRS) is commonly used to treat benign brain tumors, such as meningioma, irradiating the surrounding brain tissue can lead to perifocal edema within a few months after the procedure. Volumetric assessmen...

Artificial intelligence based assessment of clinical reasoning documentation: an observational study of the impact of the clinical learning environment on resident documentation quality.

BMC medical education
BACKGROUND: Objective measures and large datasets are needed to determine aspects of the Clinical Learning Environment (CLE) impacting the essential skill of clinical reasoning documentation. Artificial Intelligence (AI) offers a solution. Here, the ...