Chronic noncommunicable diseases (NCDS) are often characterized by gradual onset and slow progression, but the difficulty in early prediction remains a substantial health challenge worldwide. This study aims to explore the interconnectedness of disea...
Targeting ubiquitin E3 ligases is therapeutically attractive; however, the absence of an active-site pocket impedes computational approaches for identifying inhibitors. In a large, unbiased biochemical screen, we discover inhibitors that bind a crypt...
ETHNOPHARMACOLOGICAL RELEVANCE: Shengxuebao Mixture (SXB) is a traditional Chinese medicine which has been widely used on treating Chemotherapy-induced leukopenia and multiple anemia. It remains unclear whether SXB has a role in chemotherapeutic-indu...
Athletes and coaches may seek to improve running performance through adjustments to running form. Running form refers to the biomechanical characteristics of a runner's movement, and can distinguish individual runners as well as groups of runners, su...
The dorsal root ganglion (DRG) contains all primary sensory neurons, but its functional role in somatosensory and pain processing remains unclear. Recently, MR imaging techniques have been developed for objective in vivo observation of the DRG. In pa...
Dexterous manipulation remains an aspirational goal for autonomous robotic systems, particularly when learning to lift and rotate objects against gravity with intermittent finger contacts. We use model-free reinforcement learning to compare the effec...
BACKGROUND: Frailty is defined as a clinical state of increased vulnerability due to the age-associated decline of an individual's physical function resulting in increased morbidity and mortality when exposed to acute stressors. Early identification ...
Long QT syndrome (LQTS) presents a group of inheritable channelopathies with prolonged ventricular repolarization, leading to syncope, ventricular tachycardia, and sudden death. Differentiating LQTS genotypes is crucial for targeted management and tr...
INTRODUCTION: Membranous nephropathy is an autoimmune kidney disease and the most common cause of nephrotic syndrome in non-diabetic Caucasian adults. Rituximab is now recommended as first-line therapy for membranous nephropathy. However, Kidney Dise...
Cancer imaging : the official publication of the International Cancer Imaging Society
Apr 2, 2025
OBJECTIVE: This study evaluates the impact of deep learning-enhanced T1-weighted VIBE sequences (DL-VIBE) on image quality and procedural parameters during MR-guided thermoablation of liver malignancies, compared to standard VIBE (SD-VIBE).
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