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Detecting pulmonary malignancy against benign nodules using noninvasive cell-free DNA fragmentomics assay.

ESMO open
BACKGROUND: Early screening using low-dose computed tomography (LDCT) can reduce mortality caused by non-small-cell lung cancer. However, ∼25% of the 'suspicious' pulmonary nodules identified by LDCT are later confirmed benign through resection surge...

Passive wing deployment and retraction in beetles and flapping microrobots.

Nature
Birds, bats and many insects can tuck their wings against their bodies when at rest and deploy them to power flight. Whereas birds and bats use well-developed pectoral and wing muscles, how insects control their wing deployment and retraction remains...

A Machine Learning Algorithm to Predict the Starting Dose of Daptomycin.

Clinical pharmacokinetics
BACKGROUND AND OBJECTIVE: The dosage of daptomycin is usually based on body weight. However, it has been shown that this approach yields too high an exposure in obese patients. Pharmacokinetic and pharmacodynamic indexes (PK/PD) have been proposed fo...

A Novel Machine-Learning Algorithm to Predict the Early Termination of Nutrition Support Team Follow-Up in Hospitalized Adults: A Retrospective Cohort Study.

Nutrients
BACKGROUND: For hospitalized adults, it is important to initiate the early reintroduction of oral food in accordance with nutrition support team guidelines. The aim of this study was to develop and validate a machine learning-based algorithm that pre...

Tai Chi Expertise Classification in Older Adults Using Wrist Wearables and Machine Learning.

Sensors (Basel, Switzerland)
Tai Chi is a Chinese martial art that provides an adaptive and accessible exercise for older adults with varying functional capacity. While Tai Chi is widely recommended for its physical benefits, wider adoption in at-home practice presents challenge...

L Test Subtask Segmentation for Lower-Limb Amputees Using a Random Forest Algorithm.

Sensors (Basel, Switzerland)
Functional mobility tests, such as the L test of functional mobility, are recommended to provide clinicians with information regarding the mobility progress of lower-limb amputees. Smartphone inertial sensors have been used to perform subtask segment...

Predicting angiographic coronary artery disease using machine learning and high-frequency QRS.

BMC medical informatics and decision making
AIM: Exercise stress ECG is a common diagnostic test for stable coronary artery disease, but its sensitivity and specificity need to be further improved. In this paper, we construct a machine learning model for the prediction of angiographic coronary...

CT-based deep learning radiomics biomarker for programmed cell death ligand 1 expression in non-small cell lung cancer.

BMC medical imaging
BACKGROUND: Programmed cell death ligand 1 (PD-L1), as a reliable predictive biomarker, plays an important role in guiding immunotherapy of lung cancer. To investigate the value of CT-based deep learning radiomics signature to predict PD-L1 expressio...

Hybrid deep learning models for the screening of Diabetic Macular Edema in optical coherence tomography volumes.

Scientific reports
Several studies published so far used highly selective image datasets from unclear sources to train computer vision models and that may lead to overestimated results, while those studies conducted in real-life remain scarce. To avoid image selection ...

Clinical feasibility of deep learning based synthetic contrast enhanced abdominal CT in patients undergoing non enhanced CT scans.

Scientific reports
Our objective was to develop and evaluate the clinical feasibility of deep-learning-based synthetic contrast-enhanced computed tomography (DL-SynCCT) in patients designated for nonenhanced CT (NECT). We proposed a weakly supervised learning with the ...