Tumor heterogeneity poses a major challenge to the precision treatment of medulloblastoma (MB). Rapid and accurate subtyping tools are urgently needed for informed clinical decision-making. Herein, we demonstrate the utility of Raman spectroscopy (RS...
Metabolomics : Official journal of the Metabolomic Society
Sep 26, 2025
INTRODUCTION: As the most common benign gynecological tumor in women, uterine fibroids not only pose a serious threat to reproductive health but also directly impair fertility. The structural abnormalities of the uterus and metabolic disturbances the...
Honey bees () are vital pollinators essential for maintaining ecosystem stability and global food production, but they face escalating threats from pathogens, agrochemicals, and climate change. Although proteomics has advanced our understanding of be...
Physical inactivity and low fitness have become global health concerns. Metabolomics, as an integrative approach, may link fitness to molecular changes. In this study, we analyzed blood metabolomes from elderly individuals under different treatments....
Mass spectrometry imaging (MSI) has emerged as a powerful tool for spatial metabolomics, but untargeted data analysis has proven to be challenging. When combined with isotope labeling (MSI), MSI provides insights into metabolic dynamics with high sp...
Clinica chimica acta; international journal of clinical chemistry
Sep 19, 2025
Extracellular vesicles, particularly exosomes, are emerging as powerful tools in cancer research due to their role in intercellular communication and their capacity to reflect the molecular composition of their originating cells. Multi-omic approache...
Metabolomics : Official journal of the Metabolomic Society
Sep 17, 2025
INTRODUCTION AND OBJECTIVES: Oligoasthenozoospermia, characterized by a low sperm count and impaired progressive motility, significantly contributes to male infertility. This study examines the metabolic disparities between individuals with oligoasth...
Data reduction and data mining are common practices for handling large-scale data from wide-ranging sources, but high-dimensional omics and imaging data sets present difficult challenges for feature extraction and data mining due to the large number ...
Mass-based fingerprinting can characterize microorganisms; however, expansion of these methods to predict specific gene functions is lacking. Therefore, mass fingerprinting was developed to functionally profile a yeast knockout library. Matrix-assist...
This study investigated the metabolomic transformation of sea buckthorn milk fermented by Lactiplantibacillus plantarum to identify novel bioactive compounds and improve both nutritional and sensory attributes. An untargeted metabolomics workflow int...
Join thousands of healthcare professionals staying informed about the latest AI breakthroughs in medicine. Get curated insights delivered to your inbox.