AIMC Topic: Methicillin-Resistant Staphylococcus aureus
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Rapid identification of pathogenic bacteria using Raman spectroscopy and deep learning.
Nature communications
Oct 30, 2019
Raman optical spectroscopy promises label-free bacterial detection, identification, and antibiotic susceptibility testing in a single step. However, achieving clinically relevant speeds and accuracies remains challenging due to weak Raman signal from...
Escherichia coli
Staphylococcus aureus
Methicillin-Resistant Staphylococcus aureus
Candida
Bacteria
Logistic Models
Spectrum Analysis, Raman
Support Vector Machine
Klebsiella
Enterococcus
Streptococcus
Bacterial Typing Techniques
Proteus mirabilis
Bacterial Infections
Principal Component Analysis
Pseudomonas aeruginosa
Salmonella enterica
Humans
Deep Learning
Microbial Sensitivity Tests
Single-Cell Analysis
Neural Networks, Computer
Anti-Bacterial Agents
In vitro activity of tedizolid and other comparator drugs in methicillin-resistant Staphylococcus aureus isolates in skin and soft tissue infections in seven Colombian hospitals.
Biomedica : revista del Instituto Nacional de Salud
Dec 1, 2018
Introduction: Methicillin-resistant Staphylococcus aureus (MRSA) causes severe skin and soft tissue infections in hospitals and, more recently, in the community. Tedizolid is a new second-generation oxazolidinone derivative having greater in vitro po...
A new scheme for strain typing of methicillin-resistant Staphylococcus aureus on the basis of matrix-assisted laser desorption ionization time-of-flight mass spectrometry by using machine learning approach.
PloS one
Mar 13, 2018
Methicillin-resistant Staphylococcus aureus (MRSA), one of the most important clinical pathogens, conducts an increasing number of morbidity and mortality in the world. Rapid and accurate strain typing of bacteria would facilitate epidemiological inv...
Imidazolium ionic liquids as effective antiseptics and disinfectants against drug resistant S. aureus: In silico and in vitro studies.
Computational biology and chemistry
Feb 8, 2018
This paper describes Quantitative Structure-Activity Relationships (QSAR) studies, molecular docking and in vitro antibacterial activity of several potent imidazolium-based ionic liquids (ILs) against S. aureus ATCC 25923 and its clinical isolate. Sm...
Design and synthesis of cell selective α/β-diastereomeric peptidomimetic with potent in vivo antibacterial activity against methicillin resistant S. Aureus.
Bioorganic chemistry
Dec 26, 2017
Design of therapeutically viable antimicrobial peptides with cell selectivity against microorganisms is an important step towards the development of new antimicrobial agents. Here, we report four de novo designed, short amphipathic sequences based on...
Lipid Bilayers
Peptidomimetics
Phosphatidylglycerols
Stereoisomerism
Phosphatidylcholines
Erythrocytes
Acinetobacter baumannii
Hemolysis
Amino Acid Sequence
Pseudomonas aeruginosa
Keratinocytes
Enterococcus faecalis
Humans
Anti-Bacterial Agents
Female
Escherichia coli
Methicillin-Resistant Staphylococcus aureus
Mice, Inbred BALB C
Animals
Microbial Sensitivity Tests
Synergism of prenylflavonoids from Morus alba root bark against clinical MRSA isolates.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Dec 21, 2017
BACKGROUND: Clinical methicillin-resistant Staphylococcus aureus (MRSA) is a thorny problem in current anti-infective therapeutics and a challenge of new drug development. Plant prenylflavonoids possess anti-MRSA activity, but few of the prenylflavon...
Reduced methicillin-resistant Staphylococcus aureus biofilm formation in bone cavities by photodynamic therapy.
Photodiagnosis and photodynamic therapy
Dec 20, 2017
UNLABELLED: Photodynamic Therapy (PDT) is a promising alternative for the treatment of infectious bone lesions in the oral cavity. The objective of this study was to evaluate the antimicrobial effectiveness of PDT using blue LED associated with curcu...
Antibacterial mechanisms of a novel type picosecond laser-generated silver-titanium nanoparticles and their toxicity to human cells.
International journal of nanomedicine
Dec 20, 2017
In this study, we explored the antibacterial mechanisms for a novel type of Ag-TiO compound nanoparticles (NPs) produced from an Ag-TiO alloy using a picosecond laser and evaluated the toxicity of the Ag-TiO NPs to a range of human cell types. Transm...
Antimicrobial efficacy of Syzygium antisepticum plant extract against Staphylococcus aureus and methicillin-resistant S. aureus and its application potential with cooked chicken.
Food microbiology
Dec 5, 2017
For the past decades, there has been a growing demand for natural antimicrobials in the food industry. Plant extracts have attracted strong research interests due to their wide-spectrum antimicrobial activities, but only a limited number have been in...
Diaryltriazenes as antibacterial agents against methicillin resistant Staphylococcus aureus (MRSA) and Mycobacterium smegmatis.
European journal of medicinal chemistry
Dec 31, 2016
Diaryltriazene derivatives were synthesized and evaluated for their antimicrobial properties. Initial experiments showed some of these compounds to have activity against both methicillin-resistant strains of Staphylococus aureus (MRSA) and Mycobacter...
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