AIMC Topic: Methicillin-Resistant Staphylococcus aureus
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Feature selection based multivariate time series forecasting: An application to antibiotic resistance outbreaks prediction.
Artificial intelligence in medicine
Feb 19, 2020
Antimicrobial resistance has become one of the most important health problems and global action plans have been proposed globally. Prevention plays a key role in these actions plan and, in this context, we propose the use of Artificial Intelligence, ...
Epigallocatechin gallate has antibacterial and antibiofilm activity in methicillin resistant and susceptible of different lineages in non-cytotoxic concentrations.
Natural product research
Dec 9, 2019
is an opportunistic agent that can cause a variety of infections, both hospital and community-acquired. Epigallocatechin gallate (EGCG), a flavonoid present in the leaves of , has different biological activities, including antimicrobial potential. H...
Rapid identification of pathogenic bacteria using Raman spectroscopy and deep learning.
Nature communications
Oct 30, 2019
Raman optical spectroscopy promises label-free bacterial detection, identification, and antibiotic susceptibility testing in a single step. However, achieving clinically relevant speeds and accuracies remains challenging due to weak Raman signal from...
Pseudomonas aeruginosa
Microbial Sensitivity Tests
Humans
Single-Cell Analysis
Salmonella enterica
Neural Networks, Computer
Bacteria
Klebsiella
Spectrum Analysis, Raman
Anti-Bacterial Agents
Logistic Models
Enterococcus
Deep Learning
Support Vector Machine
Methicillin-Resistant Staphylococcus aureus
Escherichia coli
Streptococcus
Candida
Staphylococcus aureus
Bacterial Typing Techniques
Bacterial Infections
Proteus mirabilis
Principal Component Analysis
In vitro activity of tedizolid and other comparator drugs in methicillin-resistant Staphylococcus aureus isolates in skin and soft tissue infections in seven Colombian hospitals.
Biomedica : revista del Instituto Nacional de Salud
Dec 1, 2018
Introduction: Methicillin-resistant Staphylococcus aureus (MRSA) causes severe skin and soft tissue infections in hospitals and, more recently, in the community. Tedizolid is a new second-generation oxazolidinone derivative having greater in vitro po...
A new scheme for strain typing of methicillin-resistant Staphylococcus aureus on the basis of matrix-assisted laser desorption ionization time-of-flight mass spectrometry by using machine learning approach.
PloS one
Mar 13, 2018
Methicillin-resistant Staphylococcus aureus (MRSA), one of the most important clinical pathogens, conducts an increasing number of morbidity and mortality in the world. Rapid and accurate strain typing of bacteria would facilitate epidemiological inv...
Imidazolium ionic liquids as effective antiseptics and disinfectants against drug resistant S. aureus: In silico and in vitro studies.
Computational biology and chemistry
Feb 8, 2018
This paper describes Quantitative Structure-Activity Relationships (QSAR) studies, molecular docking and in vitro antibacterial activity of several potent imidazolium-based ionic liquids (ILs) against S. aureus ATCC 25923 and its clinical isolate. Sm...
Design and synthesis of cell selective α/β-diastereomeric peptidomimetic with potent in vivo antibacterial activity against methicillin resistant S. Aureus.
Bioorganic chemistry
Dec 26, 2017
Design of therapeutically viable antimicrobial peptides with cell selectivity against microorganisms is an important step towards the development of new antimicrobial agents. Here, we report four de novo designed, short amphipathic sequences based on...
Phosphatidylglycerols
Stereoisomerism
Acinetobacter baumannii
Hemolysis
Lipid Bilayers
Peptidomimetics
Keratinocytes
Enterococcus faecalis
Phosphatidylcholines
Erythrocytes
Anti-Bacterial Agents
Female
Animals
Microbial Sensitivity Tests
Mice, Inbred BALB C
Amino Acid Sequence
Pseudomonas aeruginosa
Escherichia coli
Methicillin-Resistant Staphylococcus aureus
Humans
Synergism of prenylflavonoids from Morus alba root bark against clinical MRSA isolates.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Dec 21, 2017
BACKGROUND: Clinical methicillin-resistant Staphylococcus aureus (MRSA) is a thorny problem in current anti-infective therapeutics and a challenge of new drug development. Plant prenylflavonoids possess anti-MRSA activity, but few of the prenylflavon...
Reduced methicillin-resistant Staphylococcus aureus biofilm formation in bone cavities by photodynamic therapy.
Photodiagnosis and photodynamic therapy
Dec 20, 2017
UNLABELLED: Photodynamic Therapy (PDT) is a promising alternative for the treatment of infectious bone lesions in the oral cavity. The objective of this study was to evaluate the antimicrobial effectiveness of PDT using blue LED associated with curcu...
Antibacterial mechanisms of a novel type picosecond laser-generated silver-titanium nanoparticles and their toxicity to human cells.
International journal of nanomedicine
Dec 20, 2017
In this study, we explored the antibacterial mechanisms for a novel type of Ag-TiO compound nanoparticles (NPs) produced from an Ag-TiO alloy using a picosecond laser and evaluated the toxicity of the Ag-TiO NPs to a range of human cell types. Transm...
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