AIMC Topic: Middle Aged

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The Predictive Value of Serum Total IgE for Antihistamine Treatment Outcomes in Chinese Patients with Chronic Spontaneous Urticaria.

Acta dermato-venereologica
Chronic spontaneous urticaria is a common skin disorder with variable treatment responses. Second-generation H1-antihistamines are the first-line treatment for chronic spontaneous urticaria, yet many patients fail to respond to licensed doses. Predic...

High-intensity interval training with robot-assisted gait therapy vs. treadmill gait therapy in chronic stroke: a randomized controlled trial.

Journal of neuroengineering and rehabilitation
OBJECTIVE: Stroke is a leading cause of long-term disability, significantly impacting patients' mobility and quality of life. Robot-assisted gait therapy (RAGT) and high-intensity interval training (HIIT) have individually shown potential in improvin...

Identification of prognostic genes related to T cell proliferation in papillary thyroid cancer based on single-cell RNA sequencing and bulk RNA sequencing data.

Clinical and experimental medicine
Papillary thyroid carcinoma (PTC) is the main pathological subtype of thyroid cancer. Given the strong association between T cells and PTC, this study focused on the prognostic value and potential molecular mechanisms of T cell proliferation-related ...

Age-related variation in hemoglobin glycation index and stroke mortality: mediation and machine learning in a cohort study.

Scientific reports
To investigate the associations between both age and the hemoglobin glycation index (HGI) and the 30-day and 1-year mortality in ischemic stroke (IS) patients and to analyze the mediating effect of the HGI on the relationship between age and mortalit...

Personalized ML-based wearable robot control improves impaired arm function.

Nature communications
Portable wearable robots offer promise for assisting people with upper limb disabilities. However, movement variability between individuals and trade-offs between supportiveness and transparency complicate robot control during real-world tasks. We ad...

Segmentation of coronary calcifications with a domain knowledge-based lightweight 3D convolutional neural network.

Computers in biology and medicine
Cardiovascular diseases are the leading cause of death in the world, with coronary artery disease being the most prevalent. Coronary artery calcifications are critical biomarkers for cardiovascular disease, and their quantification via non-contrast c...

Novel risk factors and personalized risk calculator for predicting proximal junctional kyphosis after adult spinal deformity surgery.

The bone & joint journal
AIMS: Proximal junctional kyphosis (PJK) is a prevalent and detrimental complication associated with corrective surgery for adult spinal deformity (ASD). While existing predictive models have been able to predict PJK, they have lacked individualized ...

Anemia prediction using gene expression programming (GEP) and explainable artificial intelligence approaches.

Computers in biology and medicine
Anemia being a global health disorder, affecting millions of people, especially pregnant women, children, and the elderly. Proper and timely diagnosis must be ensured to prevent its adverse effects, but the traditional diagnostic methods are very tim...

Serum metabolic patterns reveal the diagnostic and prognostic role of alanine abnormality in ocular adnexal lymphoma.

Proceedings of the National Academy of Sciences of the United States of America
Ocular adnexal lymphoma (OAL) is the most common orbital malignancy in adults. Advanced tools for precise diagnosis and prognosis of OAL are in demand. Here, the nanoparticle-enhanced laser desorption/ionization mass spectrometry was applied for the ...