AIMC Topic: Middle Aged

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Development and evaluation of interpretable machine learning regressors for predicting femoral neck bone mineral density in elderly men using NHANES data.

Biomolecules & biomedicine
Osteoporotic femoral neck fractures (OFNFs) pose a significant orthopedic challenge in the elderly population, accounting for up to 40% of all osteoporotic fractures and leading to considerable health deterioration and increased mortality. In address...

Immunometabolic alterations in type 2 diabetes mellitus revealed by single-cell RNA sequencing: insights into subtypes and therapeutic targets.

Frontiers in immunology
BACKGROUND: Type 2 Diabetes Mellitus (T2DM) represents a major global health challenge, marked by chronic hyperglycemia, insulin resistance, and immune system dysfunction. Immune cells, including T cells and monocytes, play a pivotal role in driving ...

Application of artificial intelligence to analyze data from randomized controlled trials: An example from DECAAF II.

Heart rhythm
BACKGROUND: Causal machine learning (ML) provides an efficient way of identifying heterogeneous treatment effect groups from hundreds of possible combinations, especially for randomized trial data.

Adverse Outcomes after Cemented and Cementless Primary Elective Total Hip Arthroplasty in 60,064 Matched Patients: A Study of Data from the Swedish Arthroplasty Register.

The Journal of arthroplasty
BACKGROUND: The choice between cemented and cementless fixation in primary elective total hip arthroplasty (THA) remains a subject of ongoing debate. However, comparisons between the two are subject to limited adjustments for patient characteristics,...

Integration of Deep Learning and Sub-regional Radiomics Improves the Prediction of Pathological Complete Response to Neoadjuvant Chemoradiotherapy in Locally Advanced Rectal Cancer Patients.

Academic radiology
RATIONALE AND OBJECTIVES: The precise prediction of response to neoadjuvant chemoradiotherapy is crucial for tailoring perioperative treatment in patients diagnosed with locally advanced rectal cancer (LARC). This retrospective study aims to develop ...

LMSST-GCN: Longitudinal MRI sub-structural texture guided graph convolution network for improved progression prediction of knee osteoarthritis.

Computer methods and programs in biomedicine
BACKGROUND AND OBJECTIVES: Accurate prediction of progression in knee osteoarthritis (KOA) is significant for early personalized intervention. Previous methods commonly focused on quantifying features from a specific sub-structure imaged at baseline ...

Deep Learning for Predicting Difficulty in Radical Prostatectomy: A Novel Evaluation Scheme.

Urology
OBJECTIVE: To explore new metrics for assessing radical prostatectomy difficulty through a two-stage deep learning method from preoperative magnetic resonance imaging.

Using a Deep Learning Model to Predict Postoperative Visual Outcomes of Idiopathic Epiretinal Membrane Surgery.

American journal of ophthalmology
PURPOSE: This study assessed the performance of various deep learning models in predicting the postoperative outcomes of idiopathic epiretinal membrane (ERM) surgery based on preoperative optical coherence tomography (OCT) images.

Validation of a Visual Field Prediction Tool for Glaucoma: A Multicenter Study Involving Patients With Glaucoma in the United Kingdom.

American journal of ophthalmology
PURPOSE: A previously developed machine-learning approach with Kalman filtering technology accurately predicted the disease trajectory for patients with various glaucoma types and severities using clinical trial data. This study assesses performance ...