AIMC Topic: Middle Aged

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Multi-site validation of an interpretable model to analyze breast masses.

PloS one
An external validation of IAIA-BL-a deep-learning based, inherently interpretable breast lesion malignancy prediction model-was performed on two patient populations: 207 women ages 31 to 96, (425 mammograms) from iCAD, and 58 women (104 mammograms) f...

Progression and natural history of Atypical Parkinsonism (ATPARK): Protocol for a longitudinal follow-up study from an underrepresented population.

PloS one
BACKGROUND: Atypical Parkinsonian Syndromes (APS) form the third largest group of neurodegenerative disorders including Progressive Supranuclear Palsy (PSP), Multiple System Atrophy (MSA), and Corticobasal Syndrome (CBS). These conditions are charact...

Micronutrient supplementation influences the composition and diet-originating function of the gut microbiome in healthy adults.

Clinical nutrition (Edinburgh, Scotland)
BACKGROUND & AIMS: Studies in-vitro and in animals propose that vitamins and minerals can alter the human gut microbiome. Human trials replicating these findings are scarce or used micronutrient supplementation in supraphysiological doses. We explore...

Predicting complications in breast reconstruction: External validation of a machine learning model.

Journal of plastic, reconstructive & aesthetic surgery : JPRAS
BACKGROUND: Nipple-sparing mastectomy (NSM) with immediate implant-based breast reconstruction provides aesthetic and psychosocial benefits, but nipple-areolar complex (NAC) necrosis remains a significant risk. This study externally validated a previ...

Computed tomography-derived quantitative imaging biomarkers enable the prediction of disease manifestations and survival in patients with systemic sclerosis.

RMD open
INTRODUCTION: Systemic sclerosis (SSc) is a complex inflammatory vasculopathy with diverse symptoms and variable disease progression. Despite its known impact on body composition (BC), clinical decision-making has yet to incorporate these biomarkers....

Impact of mHealth on Postoperative Quality of Life, Self-Management, and Dysfunction in Patients With Oral and Maxillofacial Tumors: Nonrandomized Controlled Trial.

JMIR mHealth and uHealth
BACKGROUND: With a focus on postoperative dysfunctions that may occur after maxillofacial tumor resection and the difficulties faced during home rehabilitation, we developed a mobile health app based on nurse-patient cooperation. The app extends reha...

Using a Multilingual AI Care Agent to Reduce Disparities in Colorectal Cancer Screening for Higher Fecal Immunochemical Test Adoption Among Spanish-Speaking Patients: Retrospective Analysis.

Journal of medical Internet research
BACKGROUND: Colorectal cancer (CRC) screening rates remain disproportionately low among Hispanic and Latino populations compared to non-Hispanic White populations. While artificial intelligence (AI) shows promise in health care delivery, concerns exi...

Regional free-water diffusion is more strongly related to neuroinflammation than neurodegeneration.

Journal of neurology
INTRODUCTION: Recent research has suggested that neuroinflammation may be important in the pathogenesis of neurodegenerative diseases. Free-water diffusion (FWD) has been proposed as a non-invasive neuroimaging-based biomarker for neuroinflammation.

Personalized machine learning models for noninvasive hypoglycemia detection in people with type 1 diabetes using a smartwatch: Insights into feature importance during waking and sleeping times.

PloS one
Hypoglycemia is a major challenge for people with diabetes. Therefore, glycemic monitoring is an important aspect of diabetes management. However, current methods such as finger pricking and continuous glucose monitoring systems (CGMS) are invasive, ...

Disrupted functional topology of the white matter connectome in rhegmatogenous retinal detachment: insights from graph theory and machine learning.

Neuroreport
BACKGROUND: Rhegmatogenous retinal detachment (RRD) is known to induce functional alterations in the gray matter regions associated with vision. However, the impact of RRD on the white matter (WM) connectome remains largely unexplored.