AIMC Topic: Models, Biological

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Development of an artificial neural network model to simulate the growth of microalga Chlorella vulgaris incorporating the effect of micronutrients.

Journal of biotechnology
Artificial neural network (ANN) models can be trained to simulate the dynamic behavior of biological systems. In the present study, an ANN model was developed upon multilayer perceptron neural network architecture with 23-20-1 configuration to predic...

A comprehensive study on the multi-class cervical cancer diagnostic prediction on pap smear images using a fusion-based decision from ensemble deep convolutional neural network.

Tissue & cell
The diagnosis of cervical dysplasia, carcinoma in situ and confirmed carcinoma cases is more easily perceived by commercially available and current research-based decision support systems when the scenario of pathologists to patient ratio is small. T...

Machine learning improves our knowledge about miRNA functions towards plant abiotic stresses.

Scientific reports
During the last two decades, human has increased his knowledge about the role of miRNAs and their target genes in plant stress response. Biotic and abiotic stresses result in simultaneous tissue-specific up/down-regulation of several miRNAs. In this ...

Variable stiffness morphing limb for amphibious legged robots inspired by chelonian environmental adaptations.

Bioinspiration & biomimetics
Robotic vehicles capable of transition from aquatic to terrestrial locomotion face considerable challenges associated with propulsive efficiency and performance in each environment. Here we present a morphing amphibious robotic limb that combines the...

Predictability of drug-induced liver injury by machine learning.

Biology direct
BACKGROUND: Drug-induced liver injury (DILI) is a major concern in drug development, as hepatotoxicity may not be apparent at early stages but can lead to life threatening consequences. The ability to predict DILI from in vitro data would be a crucia...

Prospective and External Evaluation of a Machine Learning Model to Predict In-Hospital Mortality of Adults at Time of Admission.

JAMA network open
IMPORTANCE: The ability to accurately predict in-hospital mortality for patients at the time of admission could improve clinical and operational decision-making and outcomes. Few of the machine learning models that have been developed to predict in-h...

Integration of the M6 Cyberknife in the Moderato Monte Carlo platform and prediction of beam parameters using machine learning.

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)
PURPOSE: This work describes the integration of the M6 Cyberknife in the Moderato Monte Carlo platform, and introduces a machine learning method to accelerate the modelling of a linac.

Low-power microelectronics embedded in live jellyfish enhance propulsion.

Science advances
Artificial control of animal locomotion has the potential to simultaneously address longstanding challenges to actuation, control, and power requirements in soft robotics. Robotic manipulation of locomotion can also address previously inaccessible qu...

Generalized Pharmacometric Modeling, a Novel Paradigm for Integrating Machine Learning Algorithms: A Case Study of Metabolomic Biomarkers.

Clinical pharmacology and therapeutics
There is an unmet need for identifying innovative machine learning (ML) strategies to improve drug treatment regimens and therapeutic outcomes. We investigate Generalized Pharmacometric Modeling (GPM), a novel paradigm that integrates ML algorithms w...

Deep Learning of Markov Model-Based Machines for Determination of Better Treatment Option Decisions for Infertile Women.

Reproductive sciences (Thousand Oaks, Calif.)
In this technical article, we are proposing ideas, that we have been developing on how machine learning and deep learning techniques can potentially assist obstetricians/gynecologists in better clinical decision-making, using infertile women in their...