AIMC Topic: Monocytes

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White blood cells detection and classification based on regional convolutional neural networks.

Medical hypotheses
White blood cells (WBC) are important parts of our immune system and they protect our body against infections by eliminating viruses, bacteria, parasites and fungi. There are five types of WBC. These are called Lymphocytes, Monocytes, Eosinophils, Ba...

Expression of socially sensitive genes: The multi-ethnic study of atherosclerosis.

PloS one
BACKGROUND: Gene expression may be an important biological mediator in associations between social factors and health. However, previous studies were limited by small sample sizes and use of differing cell types with heterogeneous expression patterns...

Indoleamine 2,3-Dioxygenase (IDO) Enzyme Links Innate Immunity and Altered T-Cell Differentiation in Non-ST Segment Elevation Acute Coronary Syndrome.

International journal of molecular sciences
Atherosclerosis is a chronic inflammatory disease characterized by a complex interplay between innate and adaptive immunity. Dendritic cells (DCs) play a key role in T-cell activation and regulation by promoting a tolerogenic environment through the ...

White blood cells identification system based on convolutional deep neural learning networks.

Computer methods and programs in biomedicine
BACKGROUND AND OBJECTIVES: White blood cells (WBCs) differential counting yields valued information about human health and disease. The current developed automated cell morphology equipments perform differential count which is based on blood smear im...

Sensitive detection of rare disease-associated cell subsets via representation learning.

Nature communications
Rare cell populations play a pivotal role in the initiation and progression of diseases such as cancer. However, the identification of such subpopulations remains a difficult task. This work describes CellCnn, a representation learning approach to de...

A neural joint model for entity and relation extraction from biomedical text.

BMC bioinformatics
BACKGROUND: Extracting biomedical entities and their relations from text has important applications on biomedical research. Previous work primarily utilized feature-based pipeline models to process this task. Many efforts need to be made on feature e...

Detection of S1 spike protein in CD16+ monocytes up to 245 days in SARS-CoV-2-negative post-COVID-19 vaccine syndrome (PCVS) individuals.

Human vaccines & immunotherapeutics
Despite over 13 billion SARS-CoV-2 vaccine doses administered globally, persistent post-vaccination symptoms, termed post-COVID-19 vaccine syndrome (PCVS), resemble post-acute sequelae of COVID-19 (PASC). Symptoms like cardiac, vascular, and neurolog...

Machine learning algorithm approach to complete blood count can be used as early predictor of COVID-19 outcome.

Journal of leukocyte biology
Although the SARS-CoV-2 infection has established risk groups, identifying biomarkers for disease outcomes is still crucial to stratify patient risk and enhance clinical management. Optimal efficacy of COVID-19 antiviral medications relies on early a...

Predicting apheresis yield and factors affecting peripheral blood stem cell harvesting using a machine learning model.

The Journal of international medical research
OBJECTIVE: Mobilization and collection of peripheral blood stem cells (PBSCs) are time-intensive and costly. Excessive apheresis sessions can cause physical discomfort for donors and increase the costs associated with collection. Therefore, it is ess...

Deep Learning and Single-Cell Sequencing Analyses Unveiling Key Molecular Features in the Progression of Carotid Atherosclerotic Plaque.

Journal of cellular and molecular medicine
Rupture of advanced carotid atherosclerotic plaques increases the risk of ischaemic stroke, which has significant global morbidity and mortality rates. However, the specific characteristics of immune cells with dysregulated function and proven biomar...