AIMC Topic: Neoplasm Grading

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A novel framework for esophageal cancer grading: combining CT imaging, radiomics, reproducibility, and deep learning insights.

BMC gastroenterology
OBJECTIVE: This study aims to create a reliable framework for grading esophageal cancer. The framework combines feature extraction, deep learning with attention mechanisms, and radiomics to ensure accuracy, interpretability, and practical use in tumo...

Artificial intelligence in colorectal cancer liver metastases: From classification to precision medicine.

Bioscience trends
Colorectal cancer liver metastasis (CRLM) remains the leading cause of mortality among colorectal cancer (CRC) patients, with more than half eventually developing hepatic metastases. Achieving long-term survival in CRLM necessitates early detection, ...

Enhanced hierarchical attention mechanism for mixed MIL in automatic Gleason grading and scoring.

Scientific reports
Segmenting histological images and analyzing relevant regions are crucial for supporting pathologists in diagnosing various diseases. In prostate cancer diagnosis, Gleason grading and scoring relies on the recognition of different patterns in tissue ...

Does artificial intelligence redefine nuclear-to-cytoplasmic ratio threshold for diagnosing high-grade urothelial carcinoma?

Cancer cytopathology
BACKGROUND: The Paris System (TPS) introduced standardized nuclear-to-cytoplasmic (N/C) ratio thresholds for urine cytology to improve high-grade urothelial carcinoma (HGUC) detection, but these criteria remain subjective. This study used AIxURO, an ...

Improving Deep Learning Models for Pediatric Low-Grade Glioma Tumours Molecular Subtype Identification Using MRI-based 3D Probability Distributions of Tumour Location.

Canadian Association of Radiologists journal = Journal l'Association canadienne des radiologistes
Pediatric low-grade gliomas (pLGG) are the most common brain tumour in children, and the molecular diagnosis of pLGG enables targeted treatment. We use MRI-based Convolutional Neural Networks (CNNs) for molecular subtype identification of pLGG and a...

Enhancing bone metastasis prediction in prostate cancer using quantitative mpMRI features, ISUP grade and PSA density: a machine learning approach.

Abdominal radiology (New York)
PURPOSE: Bone metastasis is a critical complication in prostate cancer, significantly impacting patient prognosis and quality of life. This study aims to enhance bone metastasis prediction using machine learning (ML) techniques by integrating dynamic...

Rapid pathologic grading-based diagnosis of esophageal squamous cell carcinoma Raman spectroscopy and a deep learning algorithm.

World journal of gastroenterology
BACKGROUND: Esophageal squamous cell carcinoma is a major histological subtype of esophageal cancer. Many molecular genetic changes are associated with its occurrence. Raman spectroscopy has become a new method for the early diagnosis of tumors becau...

Validation of a Digital Pathology-Based Multimodal Artificial Intelligence Biomarker in a Prospective, Real-World Prostate Cancer Cohort Treated with Prostatectomy.

Clinical cancer research : an official journal of the American Association for Cancer Research
PURPOSE: A multimodal artificial intelligence (MMAI) biomarker was developed using clinical trial data from North American men with localized prostate cancer treated with definitive radiation, using biopsy digital pathology images and key clinical in...

Machine learning-based reconstruction of prognostic staging for gastric cancer patients with different differentiation grades: A multicenter retrospective study.

World journal of gastroenterology
BACKGROUND: The prognosis of gastric cancer (GC) patients is poor, and an accurate prognostic staging system would help assess patients' prognostic status before treatment and determine appropriate treatment strategies.

Do explainable AI (XAI) methods improve the acceptance of AI in clinical practice? An evaluation of XAI methods on Gleason grading.

The journal of pathology. Clinical research
This work aimed to evaluate both the usefulness and user acceptance of five gradient-based explainable artificial intelligence (XAI) methods in the use case of a prostate carcinoma clinical decision support system environment. In addition, we aimed t...