AIMC Topic: Neoplasm Recurrence, Local

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Explainable and visualizable machine learning models to predict biochemical recurrence of prostate cancer.

Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico
PURPOSE: Machine learning (ML) models presented an excellent performance in the prognosis prediction. However, the black box characteristic of ML models limited the clinical applications. Here, we aimed to establish explainable and visualizable ML mo...

Boosting predictive models and augmenting patient data with relevant genomic and pathway information.

Computers in biology and medicine
The recurrence of low-stage lung cancer poses a challenge due to its unpredictable nature and diverse patient responses to treatments. Personalized care and patient outcomes heavily rely on early relapse identification, yet current predictive models,...

Image-based profiling and deep learning reveal morphological heterogeneity of colorectal cancer organoids.

Computers in biology and medicine
Patient-derived organoids have proven to be a highly relevant model for evaluating of disease mechanisms and drug efficacies, as they closely recapitulate in vivo physiology. Colorectal cancer organoids, specifically, exhibit a diverse range of morph...

A new model using deep learning to predict recurrence after surgical resection of lung adenocarcinoma.

Scientific reports
This study aimed to develop a deep learning (DL) model for predicting the recurrence risk of lung adenocarcinoma (LUAD) based on its histopathological features. Clinicopathological data and whole slide images from 164 LUAD cases were collected and us...

Identification of Genomic Signatures for Colorectal Cancer Survival Using Exploratory Data Mining.

International journal of molecular sciences
Clinicopathological presentations are critical for establishing a postoperative treatment regimen in Colorectal Cancer (CRC), although the prognostic value is low in Stage 2 CRC. We implemented a novel exploratory algorithm based on artificial intell...

Multitask deep learning for prediction of microvascular invasion and recurrence-free survival in hepatocellular carcinoma based on MRI images.

Liver international : official journal of the International Association for the Study of the Liver
BACKGROUND AND AIMS: Accurate preoperative prediction of microvascular invasion (MVI) and recurrence-free survival (RFS) is vital for personalised hepatocellular carcinoma (HCC) management. We developed a multitask deep learning model to predict MVI ...

Predicting 5-year recurrence risk in colorectal cancer: development and validation of a histology-based deep learning approach.

British journal of cancer
BACKGROUND: Accurate estimation of the long-term risk of recurrence in patients with non-metastatic colorectal cancer (CRC) is crucial for clinical management. Histology-based deep learning is expected to provide more abundant information for risk st...