BACKGROUND: Chronic Obstructive Pulmonary Disease (COPD) is a prevalent respiratory condition often accompanied by depression, which exacerbates disease burden and impairs quality of life. Early identification of depression risk in COPD patients rema...
Sarcopenia, characterized by progressive loss of muscle mass and function, is a growing public health concern. The ZJU index, a novel metabolic marker, integrates lipid metabolism and glucose regulation parameters. While its association with metaboli...
BMC medical informatics and decision making
Jul 1, 2025
OBJECTIVE: Using 2005-2018 NHANES data, this study examined the association between the visceral fat metabolism score (METS-VF) and heart failure (HF) prevalence in U.S. adults, leveraging machine learning (LightGBM/XGBoost) and SHAP for classficatio...
BACKGROUND: Brominated flame retardants (BFRs) are classified as important endocrine disruptors and persistent organic pollutants; nevertheless, there is no comprehensive investigation to evaluate the association between BFRs and hyperuricemia, and t...
BACKGROUND: Chronic Kidney Disease (CKD) affects approximately 697.5 million people worldwide. Volatile organic compounds (VOCs) are emerging as potential risk factors, but their complex relationships with CKD may be underestimated by traditional lin...
BACKGROUND: Sarcopenia is a clinicopathological condition characterized by a decrease in muscle strength and muscle mass, playing a crucial role in the prognosis of cancer. Therefore, this study aims to investigate the association between sarcopenia ...
BACKGROUND AND AIMS: Low muscle mass (LMM) is a critical complication in patients with obesity and diabetes, exacerbating metabolic and cardiovascular risks. Novel obesity indices, such as the body roundness index (BRI), conicity index, and relative ...
Osteoarthritis is a widespread chronic joint disease, becoming increasingly prevalent, particularly among individuals over the age of 45. This condition causes joint pain and dysfunction, significantly disrupting daily life. The objective of this stu...
BACKGROUND: Exposure to heavy metals has been implicated in adverse auditory health outcomes, yet the precise relationships between heavy metal biomarkers and hearing status remain underexplored. This study leverages a machine learning framework to i...
Age-related macular degeneration (AMD) is the most common cause of irreversible deterioration of vision in older adults. Previous studies have found that exposure to pesticides can lead to a worsening of AMD. In this paper, information on pesticide e...
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