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Patient Selection

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The path to precision medicine for MS, from AI to patient recruitment: an interview with Mauricio Farez and Helen Onuorah.

Communications biology
This year’s World Brain Day is focused on stopping Multiple Sclerosis (MS). Although amazing progress has resulted in the development of relatively successful MS therapies, access to such therapies is a major problem for most of the world. In additio...

Emerging role of artificial intelligence in stroke imaging.

Expert review of neurotherapeutics
: The recognition and therapy of patients with stroke is becoming progressively intricate as additional treatment choices become accessible and new associations between disease characteristics and treatment response are incessantly uncovered. Therefo...

Machine learning for selecting patients with Crohn's disease for abdominopelvic computed tomography in the emergency department.

Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver
BACKGROUND: Patients with Crohn's disease (CD) frequently undergo abdominopelvic computed tomography (APCT) in the emergency department (ED). It's essential to diagnose clinically actionable findings (CAF) as they may need immediate intervention, fre...

Optimizing hepatitis B virus screening in the United States using a simple demographics-based model.

Hepatology (Baltimore, Md.)
BACKGROUND AND AIMS: Chronic hepatitis B (CHB) affects >290 million persons globally, and only 10% have been diagnosed, presenting a severe gap that must be addressed. We developed logistic regression (LR) and machine learning (ML; random forest) mod...

Prediction of clinical trial enrollment rates.

PloS one
Clinical trials represent a critical milestone of translational and clinical sciences. However, poor recruitment to clinical trials has been a long standing problem affecting institutions all over the world. One way to reduce the cost incurred by ins...

Ranking patients on the kidney transplant waiting list based on fuzzy inference system.

BMC nephrology
BACKGROUND: Kidney transplantation is the best treatment for people with End-Stage Renal Disease (ESRD). Kidney allocation is the most important challenge in kidney transplantation process. In this study, a Fuzzy Inference System (FIS) was developed ...

Hospital Ownership, Geographic Region, Patient Age, Comorbidities, and Insurance Status Appear to Influence Patient Selection Robot-Assisted Ureteral Reimplantation for Benign Disease: A Population-Based Analysis.

Journal of endourology
Robot-assisted ureteral reimplantation (RAUR) is a relatively new minimally invasive procedure. As such, research is lacking, and the largest adult cohort studies include fewer than 30 patients. Our aim was to be the first population-based study to ...

Machine Learning Prediction of Clinical Trial Operational Efficiency.

The AAPS journal
Clinical trials are the gatekeepers and bottlenecks of progress in medicine. In recent years, they have become increasingly complex and expensive, driven by a growing number of stakeholders requiring more endpoints, more diverse patient populations, ...

The Leaf Clinical Trials Corpus: a new resource for query generation from clinical trial eligibility criteria.

Scientific data
Identifying cohorts of patients based on eligibility criteria such as medical conditions, procedures, and medication use is critical to recruitment for clinical trials. Such criteria are often most naturally described in free-text, using language fam...