AIMC Topic: Patient Selection

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Artificial intelligence in abdominal aortic aneurysm.

Journal of vascular surgery
OBJECTIVE: Abdominal aortic aneurysm (AAA) is a life-threatening disease, and the only curative treatment relies on open or endovascular repair. The decision to treat relies on the evaluation of the risk of AAA growth and rupture, which can be diffic...

Patient selection for proton therapy: a radiobiological fuzzy Markov model incorporating robust plan analysis.

Physical and engineering sciences in medicine
While proton therapy can offer increased sparing of healthy tissue compared with X-ray therapy, it can be difficult to predict whether a benefit can be expected for an individual patient. Predictive modelling may aid in this respect. However, the pre...

Prediction of progression from pre-diabetes to diabetes: Development and validation of a machine learning model.

Diabetes/metabolism research and reviews
AIMS: Identification, a priori, of those at high risk of progression from pre-diabetes to diabetes may enable targeted delivery of interventional programmes while avoiding the burden of prevention and treatment in those at low risk. We studied whethe...

Improving Clinical Trial Participant Prescreening With Artificial Intelligence (AI): A Comparison of the Results of AI-Assisted vs Standard Methods in 3 Oncology Trials.

Therapeutic innovation & regulatory science
BACKGROUND: Delays in clinical trial enrollment and difficulties enrolling representative samples continue to vex sponsors, sites, and patient populations. Here we investigated use of an artificial intelligence-powered technology, Mendel.ai, as a mea...

Out damn bot, out: Recruiting real people into substance use studies on the internet.

Substance abuse
While the Internet has become a popular and effective strategy for recruiting substance users into research, there is a large risk of recruiting duplicate individuals and Internet bots that pose as humans. Strategies to mitigate these issues are outl...

Prospective validation of a machine learning model that uses provider notes to identify candidates for resective epilepsy surgery.

Epilepsia
OBJECTIVE: Delay to resective epilepsy surgery results in avoidable disease burden and increased risk of mortality. The objective was to prospectively validate a natural language processing (NLP) application that uses provider notes to assign epileps...

Choosing Clinical Variables for Risk Stratification Post-Acute Coronary Syndrome.

Scientific reports
Most risk stratification methods use expert opinion to identify a fixed number of clinical variables that have prognostic significance. In this study our goal was to develop improved metrics that utilize a variable number of input parameters. We firs...

Can machine learning improve patient selection for cardiac resynchronization therapy?

PloS one
RATIONALE: Multiple clinical trials support the effectiveness of cardiac resynchronization therapy (CRT); however, optimal patient selection remains challenging due to substantial treatment heterogeneity among patients who meet the clinical practice ...

Improving the clinical understanding of hypertrophic cardiomyopathy by combining patient data, machine learning and computer simulations: A case study.

Morphologie : bulletin de l'Association des anatomistes
Most patients with hypertrophic cardiomyopathy (HCM), the most common genetic cardiac disease, remain asymptomatic, but others may suffer from sudden cardiac death. A better identification of those patients at risk, together with a better understandi...

Deep Learning in Personalization of Cardiovascular Stents.

Journal of cardiovascular pharmacology and therapeutics
Deep learning (DL) application has demonstrated its enormous potential in accomplishing biomedical tasks, such as vessel segmentation, brain visualization, and speech recognition. This review article has mainly covered recent advances in the principl...