Bioinformatics (Oxford, England)
Apr 3, 2023
MOTIVATION: Human traits are typically represented in both the biomedical literature and large population studies as descriptive text strings. Whilst a number of ontologies exist, none of these perfectly represent the entire human phenome and exposom...
Journal of the American Medical Informatics Association : JAMIA
Jan 18, 2023
OBJECTIVE: For the UK Biobank, standardized phenotype codes are associated with patients who have been hospitalized but are missing for many patients who have been treated exclusively in an outpatient setting. We describe a method for phenotype recog...
Nucleic acids research
Jan 6, 2023
The NHGRI-EBI GWAS Catalog (www.ebi.ac.uk/gwas) is a FAIR knowledgebase providing detailed, structured, standardised and interoperable genome-wide association study (GWAS) data to >200 000 users per year from academic research, healthcare and industr...
Bioinformatics (Oxford, England)
Jan 1, 2023
MOTIVATION: Accurately representing biological networks in a low-dimensional space, also known as network embedding, is a critical step in network-based machine learning and is carried out widely using node2vec, an unsupervised method based on biased...
Bioinformatics (Oxford, England)
Dec 13, 2022
MOTIVATION: Interactions between proteins help us understand how genes are functionally related and how they contribute to phenotypes. Experiments provide imperfect 'ground truth' information about a small subset of potential interactions in a specif...
Journal of experimental botany
Nov 2, 2022
The heading date and effective tiller percentage are important traits in rice, and they directly affect plant architecture and yield. Both traits are related to the ratio of the panicle number to the maximum tiller number, referred to as the panicle ...
BMJ health & care informatics
Nov 1, 2022
OBJECTIVE: Clinical notes contain information that has not been documented elsewhere, including responses to treatment and clinical findings, which are crucial for predicting key outcomes in patients in acute care. In this study, we propose the autom...
JCO clinical cancer informatics
Sep 1, 2022
PURPOSE: Natural language processing (NLP) applied to radiology reports can help identify clinically relevant M1 subcategories of patients with colorectal cancer (CRC). The primary purpose was to compare the overall survival (OS) of CRC according to ...
Bioinformatics (Oxford, England)
Jul 11, 2022
MOTIVATION: Medical images can provide rich information about diseases and their biology. However, investigating their association with genetic variation requires non-standard methods. We propose transferGWAS, a novel approach to perform genome-wide ...
Artificial life
Jun 28, 2022
The environment is one of the key factors in the emergence of intelligent creatures, but it has received little attention within the Evolutionary Robotics literature. This article investigates the effects of changing environments on morphological and...